Results 61 to 70 of about 83,398 (334)
Identification of Immunoreactive Tumour Antigens Using Free and Exosome-Associated Humoral Responses
Journal of Circulating Biomarkers, 2013 Altered tumour antigens can initiate cellular and humoral immune responses; however, they often fail to eliminate tumours. In humans, the presence of cancer is generally associated with the suppression of T cell activation and effector responses ...
Carolyn D. Roberson +4 more
doaj +1 more source
Strategies for deliveries of anti-cancer drugs from perspectives of a measurement theory and an adsorption theory [PDF]
arXiv, 2023 In this letter, we present anti-cancer drug delivery strategies using knowledges obtained from our recent studies. We have conducted inverse analyses of "density distributions of colloidal particles near a focused surface" and "pair potentials between the surface and the colloidal particle" using data measured by optical tweezers (OT) and atomic force ...
arxiv
Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients
Molecular Oncology, EarlyView.Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha +6 more
wiley +1 more source
Size stability and self-agglomeration of erythrocyte-derived membrane nanovesicles versus physiological extracellular vesicles [PDF]
arXiv, 2023 Extracellular vesicles (EVs) and plasma membrane-derived exosome-mimetic nanovesicles demonstrate significant potential for drug delivery. Latter synthetic provides higher throughput over physiological EVs. However they face size-stability and self-agglomeration challenges in physiological solutions to be properly characterized and addressed.
arxiv
Exosomes and Cardiovascular Protection [PDF]
Cardiovascular Drugs and Therapy, 2016 Most, if not all, cells of the cardiovascular system secrete small, lipid bilayer vesicles called exosomes. Despite technical challenges in their purification and analysis, exosomes from various sources have been shown to be powerfully cardioprotective.
Davidson, SM, Takov, K, Yellon, DM
openaire +4 more sources
Molecular Oncology, EarlyView.This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou +13 more
wiley +1 more source
Exosomes in developmental signalling [PDF]
Development, 2016 In order to achieve coordinated growth and patterning during development, cells must communicate with one another, sending and receiving signals that regulate their activities. Such developmental signals can be soluble, bound to the extracellular matrix, or tethered to the surface of adjacent cells.
Ian John McGough, Jean-Paul Vincent
openaire +4 more sources
Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer
Molecular Oncology, EarlyView.This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu +7 more
wiley +1 more source
Recent advances of emerging microfluidic chips for exosome mediated cancer diagnosis
Smart Materials in Medicine, 2021 Recent technological advances in the field of microfluidic chips have provided great opportunities to boost the development of exosome-based cancer diagnosis.
Le Wang +4 more
doaj
Cardiovascular Diabetology, 2022 Extracellular vesicles are critical mediators of cell communication. They encapsulate a variety of molecular cargo such as proteins, lipids, and nucleic acids including miRNAs, lncRNAs, circular RNAs, and mRNAs, and through transfer of these molecular ...
Valeska Ormazabal +4 more
doaj +1 more source