Results 71 to 80 of about 143,013 (333)

Laser‐Microscribed Glass Enables Surface‐Microfluidics‐Facilitated, Affordable, Rapid Cancer Diagnosis

open access: yesAdvanced Functional Materials, EarlyView.
A transparent, laser‐microscribed glass platform enables cancer diagnosis within 1 h—much faster than histology, which takes days, and free from the chemical or contrast risks of MRI or CT scans. The antibody‐functionalized rough glass surface captures viable cancer cells directly from suspension, allowing instant optical readout and offering a rapid ...
Anish Pal   +5 more
wiley   +1 more source

Exosomes regulate neurogenesis and circuit assembly. [PDF]

open access: yes, 2019
Exosomes are thought to be released by all cells in the body and to be involved in intercellular communication. We tested whether neural exosomes can regulate the development of neural circuits.
Carromeu, Cassiano   +7 more
core  

RNA Unwinding by the Trf4/Air2/Mtr4 Polyadenylation (TRAMP) Complex [PDF]

open access: yes, 2012
Many RNA-processing events in the cell nucleus involve the Trf4/Air2/Mtr4 polyadenylation (TRAMP) complex, which contains the poly(A) polymerase Trf4p, the Zn-knuckle protein Air2p, and the RNA helicase Mtr4p.
Anderson, James T.   +3 more
core   +2 more sources

Plasma Exosome-Derived SENP1 May Be a Potential Prognostic Predictor for Melanoma

open access: yesFrontiers in Oncology, 2021
ObjectiveTo evaluate plasma exosome-derived SUMO-specific protease (SENP)1 levels and assess their prognostic value in melanoma.Patients and MethodsWe extracted exosomes from the plasma of 126 melanoma patients, and identified them with transmission ...
Hejuan Hu   +9 more
doaj   +1 more source

Quantification of Exosomes [PDF]

open access: yesJournal of Cellular Physiology, 2017
Exosomes are released by cells as self‐contained vesicles with an intact lipid bilayer that encapsulates a small portion of the parent cell. Exosomes have been studied widely as information‐rich sources of potential biomarkers that can reveal cellular physiology.
Erik H, Koritzinsky   +3 more
openaire   +2 more sources

Engineering a Sonotherapeutic RBC Membrane‐Derived Nanoparticle Platform for the Treatment of Liver Cancer

open access: yesAdvanced Functional Materials, EarlyView.
Herein, an RBC membrane‐derived nanoparticle (CMN‐ICG) is engineered to efficiently deliver a sonosensitizing agent, indocyanine green (ICG), for sonotherapy of hepatocellular carcinoma (HCC). CMN‐ICG exhibits excellent cytocompatibility, significantly enhances hepatocyte uptake, and produces excessive reactive oxygen species (ROS) upon ultrasound ...
Alap Ali Zahid   +6 more
wiley   +1 more source

The Tumor Cytosol miRNAs, Fluid miRNAs, and Exosome miRNAs in Lung Cancer. [PDF]

open access: yes, 2014
The focus of this review is to provide an update on the progress of microRNAs (miRNAs) as potential biomarkers for lung cancer. miRNAs are single-stranded, small non-coding RNAs that regulate gene expression and show tissue-specific signatures ...
Haisheng eXu   +4 more
core   +2 more sources

Exosomes maintain cellular homeostasis by excreting harmful DNA from cells

open access: yesNature Communications, 2017
The role of exosomes in intercellular communication is well established, however less in known about the biological roles of exosome secretion in exosome-secreting cells.
Akiko Takahashi   +10 more
doaj   +1 more source

Enterovirus 71 non-structural protein 3A hijacks vacuolar protein sorting 25 to boost exosome biogenesis to facilitate viral replication

open access: yesFrontiers in Microbiology, 2022
Human enterovirus 71 (EV71) is one of the major agents of the hand, foot, and mouth disease (HFMD), and occasionally causes severe neurological complications.
Zhihui Ruan   +12 more
doaj   +1 more source

Unraveling the Heterogeneity of Cargo Distribution in the Exogenous Association of Proteins With Extracellular Vesicles

open access: yesAdvanced Healthcare Materials, EarlyView.
We characterized the distribution of cargo proteins associated with extracellular vesicles using various exogenous loading methods. In all cases, single‐particle analysis revealed that the distribution of protein content per EV is heterogeneous, following an exponential decay function.
Karl Normak   +6 more
wiley   +1 more source

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