Results 71 to 80 of about 97,752 (283)
Proteomic analyses of Urine Exosomes reveal New Biomarkers of Diabetes in Pregnancy. [PDF]
, 2016 ObjectiveTo evaluate 24 hour urine exosome protein content changes among pregnant US subjects with diabetes and obesity during early pregnancy.MethodsThe exosome proteome content from 24 hour urine samples of pregnant subjects with gestational diabetes ...
Aghania, Eamon +15 more
core
Progress in Exosome Isolation Techniques
Theranostics, 2017 Exosomes are one type of membrane vesicles secreted into extracellular space by most types of cells. In addition to performing many biological functions particularly in cell-cell communication, cumulative evidence has suggested that several biological ...
Pin Li +4 more
semanticscholar +1 more source
Traffic : the International Journal of Intracellular Transport, 2021 Exosomes are extracellular vesicles that in recent years have received special attention for their regulatory functions in numerous biological processes.
Javier Donoso-Quezada +2 more
semanticscholar +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Production of Living Nanoparticles for Blood Cancer Therapy [PDF]
, 2018 Current cancer therapies leave much to be desired because they are very harmful to the patient and cause a significant decrease in quality of life. Chimeric Antigen Receptors (CAR) are a promising novel approach for treating specific types of leukemia ...
Mitchell, Peter +2 more
core +1 more source
Microencapsulation technology by nature: Cell derived extracellular vesicles with therapeutic potential [PDF]
, 2013 Cell derived extracellular vesicles are submicron structures surrounded by phospholipid bilayer and released by both prokaryotic and eukaryotic cells.
Buzás, E., Falus, A., Kittel, Ágnes
core +1 more source
Cell, 2005 In the nucleus of eukaryotic cells, RNA decay in the 3'-5' direction is carried out by a complex of exonucleases called the exosome. Surprisingly, the purified exosome shows only weak activity in vitro. Two papers in this issue of Cell, by LaCava et al. (2005) and Wyers et al. (2005), and a third report by Vanacova et al.
Jensen, Torben Heick, Moore, Claire
openaire +3 more sources
Regulation of cargo selection in exosome biogenesis and its biomedical applications in cancer
Experimental and Molecular MedicineExtracellular vesicles (EVs), including exosomes, are increasingly recognized as potent mediators of intercellular communication due to their capacity to transport a diverse array of bioactive molecules.
Yu Jin Lee +2 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Towards Microfluidic-Based Exosome Isolation and Detection for Tumor Therapy.
Nano Today, 2021 Exosomes are a class of cell-secreted, nano-sized extracellular vesicles with a bilayer membrane structure of 30-150 nm in diameter. Their discovery and application have brought breakthroughs in numerous areas, such as liquid biopsies, cancer biology ...
Jie Wang +4 more
semanticscholar +1 more source