Results 101 to 110 of about 202,955 (306)
Exosomes regulate neurogenesis and circuit assembly. [PDF]
, 2019 Exosomes are thought to be released by all cells in the body and to be involved in intercellular communication. We tested whether neural exosomes can regulate the development of neural circuits.
Carromeu, Cassiano +7 more
core
High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources [PDF]
Journal of Extracellular Vesicles, 2016 Extracellular vesicles (EVs), including exosomes and microvesicles (MVs), are explored for use in diagnostics, therapeutics and drug delivery. However, little is known about the relationship of protein and lipid composition of EVs and their source cells.
Reka A. Haraszti +11 more
doaj +1 more source
Size stability and self-agglomeration of erythrocyte-derived membrane nanovesicles versus physiological extracellular vesicles [PDF]
arXiv, 2023 Extracellular vesicles (EVs) and plasma membrane-derived exosome-mimetic nanovesicles demonstrate significant potential for drug delivery. Latter synthetic provides higher throughput over physiological EVs. However they face size-stability and self-agglomeration challenges in physiological solutions to be properly characterized and addressed.
arxiv
Exosomes and Cardiovascular Protection [PDF]
Cardiovascular Drugs and Therapy, 2016 Most, if not all, cells of the cardiovascular system secrete small, lipid bilayer vesicles called exosomes. Despite technical challenges in their purification and analysis, exosomes from various sources have been shown to be powerfully cardioprotective.
Davidson, SM, Takov, K, Yellon, DM
openaire +4 more sources
Extracellular vesicles, ageing, and therapeutic interventions [PDF]
, 2018 A more comprehensive understanding of the human ageing process is required to help mitigate the increasing burden of age-related morbidities in a rapidly growing global demographic of elderly individuals.
Neytchev, Ognian +3 more
core +1 more source
Exosomes in developmental signalling [PDF]
Development, 2016 In order to achieve coordinated growth and patterning during development, cells must communicate with one another, sending and receiving signals that regulate their activities. Such developmental signals can be soluble, bound to the extracellular matrix, or tethered to the surface of adjacent cells.
Ian John McGough, Jean-Paul Vincent
openaire +4 more sources
Pseudotyping exosomes for enhanced protein delivery in mammalian cells. [PDF]
, 2017 Exosomes are cell-derived nanovesicles that hold promise as living vehicles for intracellular delivery of therapeutics to mammalian cells. This potential, however, is undermined by the lack of effective methods to load exosomes with therapeutic proteins ...
Li, Lingxuan +5 more
core
Microvesicles and exosomes: new players in metabolic and cardiovascular disease [PDF]
, 2016 The past decade has witnessed an exponential increase in the number of publications referring to extracellular vesicles (EVs). For many years considered to be extracellular debris, EVs are now seen as novel mediators of endocrine signalling via cell-to ...
Charlotte Lawson +21 more
core +2 more sources
Stem Cells International, 2019 Mesenchymal stem cells derived from human umbilical cord (hucMSCs) are considered a promising tool for regenerative medicine. circRNAs as newly discovered noncoding RNAs are involved in multiple biological processes.
Lunyu Yang +8 more
doaj +1 more source
Cells, 2019 Exosomes are extracellular vesicles that contain a specific composition of proteins, lipids, RNA, and DNA. They are derived from endocytic membranes and can transfer signals to recipient cells, thus mediating a novel mechanism of cell-to-cell ...
Sangiliyandi Gurunathan +4 more
semanticscholar +1 more source