Results 221 to 230 of about 177,584 (349)

Disrupting Lipid Raft Microdomains to Block Polyploid Giant Cancer Cell Budding and Enhance Radiotherapy Response

Advanced Science, EarlyView.
Radiation induces polyploid giant cancer cells (PGCCs) that regenerate tumors through virus‐like budding. This process depends on a SNCG–FLOT2–CHMP4B signaling axis functioning in lipid raft microdomains. Disrupting these domains using statins or anti‐PCSK9 antibodies blocks PGCC budding, suppresses tumor repopulation, and enhances radiotherapy ...
Zheng Deng, Haoran Sun, Jin Cheng, Ruyi Zhao, Jianzhu Xie, Yanwei Song, Yucui Zhao, Chenwei Lin, Binjie Hu, Yanping Gong, Jun Lin, Sijia He, Yuntao Luo, Minghui Zhao, Yiwei Wang, Ming Jiao, Yuqin Yang, Jikun Li, Shujie Xia, Chuanyuan Li, Qian Huang   +20 more
wiley   +1 more source

Exosomes are involved in total body irradiation-induced intestinal injury in mice

, 2021
Hang Li, Mian Jiang, Shu-ya Zhao, Shuqin Zhang, Lu Lu, Xin He, Guoxing Feng, Xin Wu, Saijun Fan   +8 more
openalex   +2 more sources

Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis

Cell Research, 2015
Yan Li, Qiupeng Zheng, Chunyang Bao, Shuyi Li, Weijie Guo, Jiang-xia Zhao, Di Chen, J. Gu, Xianghuo He, Shenglin Huang   +9 more
semanticscholar   +1 more source

Targeting the Hyperglycemic Pre‐Metastatic Niche to Prevent Breast Cancer Bone Metastasis: Mechanisms and Therapeutic Strategies

Advanced Science, EarlyView.
Abstract The recent pioneering study by Ye et al. (Adv Sci. 2025;12(37):e0504924) provides compelling evidence that systemic hyperglycemia orchestrates a pre‐metastatic niche (PMN) in bone, promoting breast cancer metastasis and identifying Receptor for Advanced Glycation End‐products (RAGE) inhibition as a viable therapeutic strategy.
DuJiang Yang, Jiexiang Yang, GuoYou Wang
wiley   +1 more source

Author Correction: Cryogenic electron microscopy reveals morphologically distinct subtypes of extracellular vesicles among porcine ejaculate fractions

Scientific Reports
Ana Parra, Isabel Barranco, Pablo Martínez‑Díaz, Esperanza González, Oihane E. Albóniga, Diana Cabrera, Juan M. Falcón‑Pérez, Jordi Roca   +7 more
doaj   +1 more source

Correction: Efficient methods of isolation and purification of extracellular vesicles. [PDF]

Nano Converg
Kim T, Hong JW, Lee LP.
europepmc   +1 more source

Migrasomes in Ischemic Stroke: Molecular Landscape and Pathophysiological Impact

Advanced Science, EarlyView.
Multi‐omics profiling of stroke patients exposes systemic molecular fingerprints of immune activation, oxidative stress and metabolic collapse. Complement and coagulation cascade, and cholesterol metabolism emerge as shared functional hallmarks of plasma migrasomes in stroke patients and migrasomes isolated from experimental stroke mice.
Huifen Zhou, Yingying Zhang, Peng Zhou, Haofang Wan, Lingling Li, Bin Xu, Yuping Wan, Yingming Song, Yi Kang, Hongbo Zhang, Min Shi, Qun Hou, Jiehong Yang, Chen Ding, Wei Fu, Buchang Zhao, Haitong Wan   +16 more
wiley   +1 more source

Exosome-Enhanced Injectable Hydrogels: A Comprehensive Review on Their Emerging Role in Wound Healing. [PDF]

Health Sci Rep
Astaneh ME, Baldaniya L, Singh A, Hussen A, Hashemzadeh A, Fereydouni N.   +5 more
europepmc   +1 more source

A TtAgo‐Driven Autocatalytic Circuit with Thermal‐Enhanced Kinetics for One‐Pot Nucleic Acid Detection

Advanced Science, EarlyView.
This study proposes a universal catalytic DNA circuits termed TACTIC (Thermus thermophilus protein‐driven autocatalytic circuit) for one‐pot detection of DNA and RNA in multiple clinical samples. Integrated with machine learning, TACTIC accurately profile the distinct expression of four extracellular vesicle‐derived miRNAs across different samples and ...
Zuowei Xie, Ruijia Deng, Ben Niu, Yingjie Yang, Shuang Zhao, Hongzhao Yang, Meilin Gong, Jie Luo, Yu Tang, Jing Sheng, Yan Pi, Ming Chen, Kai Chang   +12 more
wiley   +1 more source

Single-Exosome SERS Detection by Means of a Flexible Metasurface. [PDF]

Biosensors (Basel)
Mochalov K, Korzhov D, Shestopalova M, Ivanov A, Afanasev K, Smyk A, Shurygin A, Sarychev AK.   +7 more
europepmc   +1 more source