Results 251 to 260 of about 165,875 (347)

Drosophila gene tazman, an orthologue of the yeast exosome component Rrp44p/Dis3, is differentially expressed during development [PDF]

, 2005
Fátima Cairrão, Cecília M. Arraiano, Sarah F. Newbury   +2 more
openalex   +1 more source

Pancreatic Cancer‐Derived Extracellular Vesicles Enriched with miR‐223‐5p Promote Skeletal Muscle Wasting Associated with Cachexia

Advanced Science, EarlyView.
EVs and EV‐microRNAs (miRNAs) mediate PDAC‐skeletal muscle communication. miR‐223‐5p reduces METTL14 transcription by targeting MAFA, which subsequently decreases m6A methylation in skeletal muscles, ultimately leading to muscle wasting. This study highlights the absorption of miRNA in PDAC‐derived EVs by skeletal muscles and reveals a previously ...
Kangjing Xu, Rongxi Shen, Li Zhang, Xuejin Gao, Xinbo Wang, Changhua Zhang, Xi Chen, Xinying Wang   +7 more
wiley   +1 more source

MiRNA-29b accelerates the PDGF in exosomes and stimulates hepatic stellate cells to promote liver fibrosis in biliary atresia. [PDF]

Eur J Med Res
Liao X, Liu R, Zhou T, Zhao X, Xiong X, Zhang K, Zheng Z, Xia X, Tang C, Gong Y, Du Q, Huang L, Zhu D, Zhou W, Liu Y, Jin Z.   +15 more
europepmc   +1 more source

Exosome Secretion: The Art of Reutilizing Nonrecycled Proteins?

, 2004
Aude De Gassart, Charles Géminard, Dick Hoekstra, Michel Vidal   +3 more
openalex   +1 more source

Alzheimer's disease β-amyloid peptides are released in association with exosomes [PDF]

, 2006
Lawrence Rajendran, Masanori Honsho, Tobias Zahn, Patrick Keller, Kathrin Geiger, Paul Verkade, Kai Simons   +6 more
openalex   +1 more source

Neutrophil‐Mimicking Nanomedicine Eliminates Tumor Intracellular Bacteria and Enhances Chemotherapy on Liver Metastasis of Colorectal Cancer

Advanced Science, EarlyView.
Fusobacterium nucleatum (Fn) enrichment has been identified in colorectal cancer and its liver metastases. This study develops neutrophil‐mimicking nanoparticles with multiple targeting capabilities encapsulating metronidazole and oxaliplatin for antibacterial and anticancer purposes. This approach reverses the epithelial mesenchymal transition process
Yanan Niu, Xu Zhao, Yong Li, Xiaoya Ma, Weifeng Yang, Jie Ma, Wanglin Li, Wei Yuan   +7 more
wiley   +1 more source

Ginseng-Derived Exosomes Attenuate Immune Evasion in NSCLC via PD-L1 Modulation. [PDF]

Cancer Manag Res
Zhu LJ, Chen XQ, Lin QY, Feng JN, Yuan SF.   +4 more
europepmc   +1 more source

Autophagy‐Mediated Suppression of Tumor Growth by Food‐Grade Lipid Nanoparticles in Mice

Advanced Science, EarlyView.
This work reveals a novel extracellular nanoparticle transport and metabolic pathway. Following cellular uptake, Food‐grade lipid nanoparticles (FLNs) selectively fuse with lipid droplets (LDs) rather than lysosomes, driving LDs accumulation. This process activates autophagy through the AMPK‐mTOR‐ULK1 signaling axis, facilitating tumor progression ...
Chenglu Peng, Bing Jiang, Wei Lu, Przemyslaw Zalewski, Jun He, Xiaoyang Li, Yiping Cao, Yiguo Zhao, Cuixia Sun, Katsuyoshi Nishinari, Yapeng Fang   +10 more
wiley   +1 more source

Exosomes from high-altitude cerebral edema patients induce cognitive dysfunction by altering oxidative stress responses in mice. [PDF]

Transl Psychiatry
Fu Q, Qiu R, Tang Q, Li X, Li Y, Qin Y, Li Q, Yao J, Jiang Z, Xu H, Cheng Y.   +10 more
europepmc   +1 more source

Human iPSCs Derived MSCs‐Secreted Exosomes Modulate Senescent Nucleus Pulposus Cells Induced Macrophage Polarization via Metabolic Reprogramming to Mitigate Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Senescent nucleus pulposus cells drive inflammatory M1 macrophage polarization, exacerbating intervertebral disc degeneration (IDD). Conversely, M1 macrophages accelerate NP cell senescence, creating a vicious cycle. iPSCs‐derived mesenchymal stem cell (iMSCs) exosomes break this loop by delivering miR‐100‐5p to suppress mTORC1/glycolysis in ...
Qian Xiang, Jiawen Zhan, Shuo Tian, Yongzhao Zhao, Zhenquan Wu, Jialiang Lin, Longting Chen, Longjie Wang, Shuai Jiang, Zhuoran Sun, Weishi Li   +10 more
wiley   +1 more source