Results 81 to 90 of about 202,955 (306)

Exosomes containing HIV protein Nef reorganize lipid rafts potentiating inflammatory response in bystander cells. [PDF]

, 2019
HIV infection has a profound effect on "bystander" cells causing metabolic co-morbidities. This may be mediated by exosomes secreted by HIV-infected cells and containing viral factors.
Brichacek, Beda, Bukrinsky, Michael, Ditiatkovski, Michael, Dragoljevic, Dragana, Dubrovsky, Larisa, Fu, Ying, Hoang, Anh, Horvath, Anelia, Low, Hann, Meikle, Peter J, Miller, Yury I, Mukhamedova, Nigora, Murphy, Andrew, Ohkawa, Ryunosuke, Pushkarsky, Tatiana, Sviridov, Dmitri   +15 more
core   +3 more sources

Exosome and Exosomal MicroRNA: Trafficking, Sorting, and Function

Genomics, Proteomics & Bioinformatics, 2015
Abstract Exosomes are 40–100 nm nano-sized vesicles that are released from many cell types into the extracellular space. Such vesicles are widely distributed in various body fluids. Recently, mRNAs and microRNAs (miRNAs) have been identified in exosomes, which can be taken up by neighboring or distant cells and subsequently modulate ...
Zhang, Jian, Li, Sha, Li, Lu, Li, Meng, Guo, Chongye, Yao, Jun, Mi, Shuangli   +6 more
openaire   +3 more sources

Exosomal αvβ6 integrin is required for monocyte M2 polarization in prostate cancer [PDF]

, 2018
Therapeutic approaches aimed at curing prostate cancer are only partially successful given the occurrence of highly metastatic resistant phenotypes that frequently develop in response to therapies.
Altieri, Dario C., Bowler, Nicholas, Craig Hooper, D., Dutta, Anindita, Ertel, Adam, Fedele, Carmine, Forsberg, Flemming, Fortina, Paolo, Gabrilovich, Dmitry I., Harshyne, Larry A., Kean, Rhonda B., Kelly, William K., Kossenkov, Andrew V., Krishn, Shiv Ram, Kurtoglu, Senem, Languino, Lucia R., Liu, Qin, Lu, Huimin, Speicher, David W., Stanczak, Maria, Tang, Hsin-Yao, Wang, Kerith, Weinreb, Paul H., Yu, Lei   +23 more
core   +1 more source

Development of an Organ-Directed Exosome-Based siRNA-Carrier Derived from Autologous Serum for Lung Metastases and Testing in the B16/BL6 Spontaneous Lung Metastasis Model

Pharmaceutics, 2022
Exosomes are nano-sized extracellular vesicles that are known to carry various messages to distant cells. It was recently reported that cancer-derived exosomes are orientated to metastatic organs. However, there are no reports on drug carrier development
Mai Hazekawa, Takuya Nishinakagawa, Masato Hosokawa, Daisuke Ishibashi   +3 more
doaj   +1 more source

Assessment of bovine milk exosome preparation and lyophilized powder stability

Journal of Extracellular Biology
Exosomes are cell‐derived nanovesicles that play a crucial role in intercellular communication, presenting promising potential as biomarkers and therapeutic agents.
Lu Lu, Chunle Han, Miao Wang, Huanqing Du, Ning Chen, Mengya Gao, Na Wang, Dongli Qi, Wei Bai, Jianxin Yin, Fengwei Dong, Tianshi Li, Xiaohu Ge   +12 more
doaj   +1 more source

The role of mesenchymal stem cells derived exosomes as a novel nanobiotechnology target in the diagnosis and treatment of cancer

Frontiers in Bioengineering and Biotechnology, 2023
Mesenchymal stem cells (MSCs), one of the most common types of stem cells, are involved in the modulation of the tumor microenvironment (TME). With the advancement of nanotechnology, exosomes, especially exosomes secreted by MSCs, have been found to play
You Zhou, Yuqing Dong, Aixue Zhang, Jibin Wu, Qiang Sun   +4 more
doaj   +1 more source

DLDNN: Deterministic Lateral Displacement Design Automation by Neural Networks [PDF]

arXiv, 2022
Size-based separation of bioparticles/cells is crucial to a variety of biomedical processing steps for applications such as exosomes and DNA isolation. Design and improvement of such microfluidic devices is a challenge to best answer the demand for producing homogeneous end-result for study and use.
arxiv  

Exosomes, a New Star for Targeted Delivery

Frontiers in Cell and Developmental Biology, 2021
Exosomes are cell-secreted nanoparticles (generally with a size of 30–150 nm) bearing numerous biological molecules including nucleic acids, proteins and lipids, which are thought to play important roles in intercellular communication.
Huizhi Chen, Liyan Wang, Xinling Zeng, H. Schwarz, H. S. Nanda, Xinsheng Peng, Yubin Zhou   +6 more
semanticscholar   +1 more source

Roles of Exosomes and Exosomal MicroRNAs in Postoperative Sleep Disturbance

Nature and Science of Sleep, 2021
Postoperative sleep disturbance (PSD) often occurs in elderly patients after major surgery and exerts harmful effects on postoperative recovery. PSD may increase the incidence of postoperative fatigue, severe anxiety and depression, pain sensitivity, and cognitive dysfunction, which can cause or aggravate neurodegenerative diseases via amyloid ...
Junchao Zhu, Xiangyi Gu
openaire   +4 more sources

tRNA Profiling of Mesenchymal Stem Cell Exosome [PDF]

, 2018
Background: Exosomes have great potential in regenerative medicine through the transfer of their bioactive cargos, such as RNA. tRF RNA and tiRNA are tRNAderived non-coding RNA.
San, Khin MiMi
core   +1 more source