Results 81 to 90 of about 222,944 (406)
Role of Exosomes and Exosomal microRNAs in Cancer
Future Science OA, 2020 A growing body of evidence indicates that exosomes play a critical role in the cell-cell communication process. Exosomes are biological nanoparticles with an average diameter of 30-100 nm in size and are produced by almost all cell types in the human body; however, cancer cells contain higher concentrations of exosomes than healthy cells.
openaire +4 more sources
Exosomal αvβ6 integrin is required for monocyte M2 polarization in prostate cancer [PDF]
, 2018 Therapeutic approaches aimed at curing prostate cancer are only partially successful given the occurrence of highly metastatic resistant phenotypes that frequently develop in response to therapies.
Altieri, Dario C. +23 more
core +1 more source
Exosome and Exosomal MicroRNA: Trafficking, Sorting, and Function
Genomics, Proteomics & Bioinformatics, 2015 Abstract Exosomes are 40–100 nm nano-sized vesicles that are released from many cell types into the extracellular space. Such vesicles are widely distributed in various body fluids. Recently, mRNAs and microRNAs (miRNAs) have been identified in exosomes, which can be taken up by neighboring or distant cells and subsequently modulate ...
Zhang, Jian +6 more
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Frontiers in Bioengineering and Biotechnology, 2023 Mesenchymal stem cells (MSCs), one of the most common types of stem cells, are involved in the modulation of the tumor microenvironment (TME). With the advancement of nanotechnology, exosomes, especially exosomes secreted by MSCs, have been found to play
You Zhou +4 more
doaj +1 more source
Microglial exosomes facilitate α-synuclein transmission in Parkinson's disease.
Brain : a journal of neurology, 2020 Accumulation of neuronal α-synuclein is a prominent feature in Parkinson's disease. More recently, such abnormal protein aggregation has been reported to spread from cell to cell and exosomes are considered as important mediators.
Min Guo +7 more
semanticscholar +1 more source
Genotoxic stress modulates the release of exosomes from multiple myeloma cells capable of activating NK cell cytokine production: role of HSP70/TLR2/NF-kB axis [PDF]
, 2017 Exosomes are a class of nanovesicles formed and released through the late endosomal compartment and represent an important mode of intercellular communication.
ABRUZZESE, MARIA PIA +17 more
core +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Assessment of bovine milk exosome preparation and lyophilized powder stability
Journal of Extracellular BiologyExosomes are cell‐derived nanovesicles that play a crucial role in intercellular communication, presenting promising potential as biomarkers and therapeutic agents.
Lu Lu +12 more
doaj +1 more source
High-resolution proteomic and lipidomic analysis of exosomes and microvesicles from different cell sources [PDF]
Journal of Extracellular Vesicles, 2016 Extracellular vesicles (EVs), including exosomes and microvesicles (MVs), are explored for use in diagnostics, therapeutics and drug delivery. However, little is known about the relationship of protein and lipid composition of EVs and their source cells.
Reka A. Haraszti +11 more
doaj +1 more source
Sensors, 2022 Dielectrophoresis (DEP) refers to a type of electrical motion of dielectric particles. Because DEP is caused by particle polarization, it has been utilized to characterize particles.
Hao Chen +4 more
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