Results 111 to 120 of about 19,438 (226)

GRP78 Nanobody‐Directed Immunotoxin Activates Innate Immunity Through STING Pathway to Synergize Tumor Immunotherapy

Advanced Science
The lack of targetable antigens poses a significant challenge in developing effective cancer‐targeted therapies. Cell surface translocation of endoplasmic reticulum (ER) chaperones, such as glucose‐regulated protein 78 (GRP78), during malignancy, drug ...
Huifang Wang, Runhua Zhou, Chengchao Xu, Lingyun Dai, Rui Hou, Liuhai Zheng, Chunjin Fu, Guangwei Shi, Jingwei Wang, Yang Li, Jinpeng Cen, Xiaolong Xu, Le Yu, Yilei Li, Jigang Wang, Qingfeng Du, Zhijie Li   +16 more
doaj   +1 more source

Transverse myelitis secondary to Melioidosis; A case report

BMC Infectious Diseases, 2012
Background Melioidosis has become an emerging infection in Sri Lanka; a country which is considered non endemic for it. Paraplegia due to Burkholderia pseudomallei is a very rare entity encountered even in countries where the disease is endemic.
Nandasiri Shanika, Wimalaratna Harith, Manjula Muditha, Corea Enoka   +3 more
doaj   +1 more source

Group A β-Hemolytic Streptococcus Meningitis: Clinical and Microbiological Features of Nine Cases [PDF]

, 2017
Group A β-hemolytic streptococcus (GAS) meningitis is a rare disease in adults. We conducted a retrospective study to describe clinical and microbiological features of nine cases of GAS meningitis in Switzerland.
Auckenthaler, Raymond, Garbino, Jorge, Kaiser, Laurent, Lew, Daniel, Malinverni, Raffaele, Rohner, Peter, Sommer, Richard   +6 more
core  

Detection of Exotoxin A, Y, T, U, S genes of Pseudomonas aeruginosa Isolates Resistant to Third-Generation Cephalosporins in Clinical Samples of Hospitalized Patients in Hospitals of Qom City, Iran

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2016
Background and Objectives: One of the most common problems in hospitals is infections caused by Pseudomonas aeruginosa that is an opportunistic pathogen for humans.
Seyyed Soheil Aghaei, Ali Javadi, Yaser Sharifi, Abbas Morovvati   +3 more
doaj  

Role of speA Gene Expression in Streptococcus pyogenes of Infectious Diseases

Al-SalamJournal for Medical Science
range of clinical conditions, ranging from mild (i.e. pharyngitis) to severe and life-threatening diseases like necrotizing fasciitis and streptococcal toxic shock syndrome.
Rawaa T. Abdulghafoor
doaj   +1 more source

Tofacitinib to prevent anti-drug antibody formation against LMB-100 immunotoxin in patients with advanced mesothelin-expressing cancers

Frontiers in Oncology
BackgroundLMB-100 is a mesothelin (MSLN)-targeting recombinant immunotoxin (iTox) carrying a Pseudomonas exotoxin A payload that has shown promise against solid tumors, however, efficacy is limited by the development of neutralizing anti-drug antibodies (
Nebojsa Skorupan, Cody J. Peer, Xianyu Zhang, Hyoyoung Choo-Wosoba, Mehwish I. Ahmad, Min-Jung Lee, Shraddha Rastogi, Nahoko Sato, Yunkai Yu, Guillaume Joe Pegna, Seth M. Steinberg, Shelley S. Kalsi, Liang Cao, William D. Figg, Jane B. Trepel, Ira Pastan, David FitzGerald, Christine Alewine   +17 more
doaj   +1 more source

Partial purification and properties of plasmonigen fractionated from horse serum and activated via staphylokinase [PDF]

, 1951
Thesis (M.A.)--Boston ...
Kaplan, Carl
core   +1 more source

Group A streptococcus cell-associated pathogenic proteins as revealed by growth in hyaluronic acid enriched media. [PDF]

, 2007
Ashbaugh, Berge, Burova, Caparon, Carapetis, Chaussee, Collin, Cunningham, Dixon, Dryla, Eng, Ferretti, Fiona M. McDonald, Frithz, Gary W. Black, Gasteiger, Gomi, Graham, Graham, Green, Guyre, Houtman, Husmann, Hynes, Hynes, Hynes, Ian Humphery-Smith, Johansson, Kansal, La Penta, Laurent, Lei, Levin, LiCalsi, Lukomski, Malke, Meng Zhang, Mims, Musser, Na, Nannini, Okada, Pancholi, Pancholi, Pancholi, Podbielski, Raeder, Raeder, Ratnayake-Lecamwasam, Senadheera, Shane S. Sturrock, Simon J. Charnock, Sjobring, Smith, Teng, Terao, Thongboonkerd, Voyich, Wilkins, Wilkins   +59 more
core   +1 more source

Nematicidal activity of Bacillus thuringiensis isolates [PDF]

, 1995
L'activité nématicide de mélanges de spores et d'inclusions cristallines de trois isolats de #Bacillus thuringiensis$ envers les juvéniles et les adultes de #Caenorhabditis elegans$ est étudiée.
Arnaut, G., Borgonie, G., De Waele, D., Leyns, F.   +3 more
core  

Proinflammatory synergy between protease and superantigen streptococcal pyogenic exotoxins

Infection and Immunity
Streptococcal pyogenic exotoxins (Spe proteins) secreted by Streptococcus pyogenes (group A Streptococcus, GAS) are responsible for scarlet fever and streptococcal toxic shock syndrome.
Anders F. Johnson, Summer D. Bushman, Doris L. LaRock, Juan Manuel Díaz, John K. McCormick, Christopher N. LaRock   +5 more
doaj   +1 more source