Results 141 to 150 of about 11,626 (172)
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CD8+ T-cell mediated tumor protection by Pseudomonas exotoxin fused to ovalbumin in C57BL/6 mice
Surgery, 2003Pseudomonas exotoxin (PE) is a 66 kDa bacterial toxin that is able to bind to mammalian cells, undergo receptor mediated endocytosis, and translocate its C-terminal catalytic domain into the cytosol. We investigated whether PE could be used in vivo to deliver CD8+ T-cell epitopes to the MHC-class I antigen presentation pathway to trigger a specific ...
Juan C, Becerra +4 more
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Annals of the New York Academy of Sciences, 1975
The immune response at the level of individual immunocytes to the somatic lipopolysaccharide antigen derived from whole Vibrio cholerae and to the purified protein exotoxin from this organism were studied in terms of the role of T- and B-lymphocytes. By adoptive cell transfer studies with irradiated recipient mice, it was shown that normal spleen cells
Kateley, J R, Patel, C B, Friedman, H
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The immune response at the level of individual immunocytes to the somatic lipopolysaccharide antigen derived from whole Vibrio cholerae and to the purified protein exotoxin from this organism were studied in terms of the role of T- and B-lymphocytes. By adoptive cell transfer studies with irradiated recipient mice, it was shown that normal spleen cells
Kateley, J R, Patel, C B, Friedman, H
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Molecular Microbiology, 1997
Streptococcus pyogenes that produces the bacterial superantigen streptococcal pyrogenic exotoxin A (SpeA) is associated with outbreaks of streptococcal toxic shock syndrome (STSS) in the United States and Europe. SpeA stimulates Vβ2.1, 12.2, 14.1, and 15.1‐positive T cells, and the lymphokine production from the activated T cells is believed to result
J B, Kline, C M, Collins
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Streptococcus pyogenes that produces the bacterial superantigen streptococcal pyrogenic exotoxin A (SpeA) is associated with outbreaks of streptococcal toxic shock syndrome (STSS) in the United States and Europe. SpeA stimulates Vβ2.1, 12.2, 14.1, and 15.1‐positive T cells, and the lymphokine production from the activated T cells is believed to result
J B, Kline, C M, Collins
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Streptococcal pyrogenic exotoxin a induces regulatory T cells via TNF-α-TNFR2 signaling
Medical Microbiology and ImmunologyBacterial superantigens are potent immune activators that trigger T cell proliferation and intensive release of cytokines, leading to toxic shock syndrome. Also, they impair host immune responses, increasing bacterial carriage and transmission. Several studies proposed that superantigens can induce regulatory T (Treg) cells, which may suppress immune ...
Chun-Hao, Lu +6 more
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American Journal of Rhinology & Allergy, 2011
Background Staphylococcus aureus exotoxins (SEs) have been implicated in the pathogenesis of nasal polyps (NPs) in patients with chronic rhinosinusitis (CRS). The aim of this study was to identify the correlation between SEs and T cells in NPs. Methods
Seon Tae, Kim +4 more
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Background Staphylococcus aureus exotoxins (SEs) have been implicated in the pathogenesis of nasal polyps (NPs) in patients with chronic rhinosinusitis (CRS). The aim of this study was to identify the correlation between SEs and T cells in NPs. Methods
Seon Tae, Kim +4 more
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Effect of Pseudomonas aeruginosa exotoxin A on CD3-induced human T-cell activation.
Immunology letters, 1998The effect of Pseudomonas aeruginosa (PA) exotoxin A (P-ExA) on CD3-induced T-cell activation was studied on the level of T-cells (proliferation, synthesis of interleukin (IL)-2, expression of IL-2R complex, ICAM-1,2 and LFA-1 molecules), and on the level of monocytes (expression of ICAM-1,2, LFA-1 molecules, as well as FcRI and CD14 receptors).
J, Michalkiewicz +6 more
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Mechanisms of Resistance to Immunotoxins Containing Pseudomonas Exotoxin A in Cancer Therapy
Biomolecules, 2020Michael Dieffenbach, Ira Pastan
exaly
Production of heat-stable exotoxin by Bacillus thuringiensis and related bacteria
Journal of Invertebrate Pathology, 1981Michio Ohba, Keiô Aizawa
exaly
Correlation between serovars of Bacillus thuringiensis and type I β-exotoxin production
Journal of Invertebrate Pathology, 2003Juan Ferré +2 more
exaly