Periodontology 2000, EarlyView., 2023 Abstract This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis‐centered interpretation.
Georgios N. Belibasakis +5 more
wiley +1 more source
Nonspecific T-lymphocyte mitogenesis by pyrogenic exotoxins from group A streptococci and Staphylococcus aureus [PDF]
Infection and Immunity, 1979 Group A streptococcal pyrogenic exotoxins types A, B, and C and staphylococcal pyrogenic exotoxin were shown to be potent nonspecific T-lymphocyte mitogens. Adherent cell populations did not significantly affect the nonspecific mitogenicity.
P M, Schlievert +2 more
openaire +2 more sources
Membrane perturbing properties of toxin mycolactone from Mycobacterium ulcerans. [PDF]
PLoS Computational Biology, 2018 Mycolactone is the exotoxin produced by Mycobacterium ulcerans and is the virulence factor behind the neglected tropical disease Buruli ulcer. The toxin has a broad spectrum of biological effects within the host organism, stemming from its interaction ...
Cesar A López +4 more
doaj +1 more source
First Description of Mergibacter septicus Isolated from a Common Tern (Sterna hirundo) in Germany
Pathogens, 2023 Mergibacter septicus (M. septicus), previously known as Bisgaard Taxon 40, is a recently described species within the Pasteurellaceae family. In this study, we present a M. septicus strain isolated from a common tern (Sterna hirundo) chick that died just
Mostafa Y. Abdel-Glil +3 more
doaj +1 more source
Control of the Colorado Potato Beetle (Coleoptera: Chrysomelidae) on Tomatoes with \u3ci\u3eBacillus Thuringiensis\u3c/i\u3e Var. \u3ci\u3eThuringiensis\u3c/i\u3e [PDF]
, 2017 (excerpt) The Colorado potato beetle, Leptinotarsa decemlineata (Say), is a serious pest of tomatoes grown in this country. This beetle is also developing resistance to several classes of chemical insecticides including most of the carbamates ...
Cantelo, W. W, Cantwell, G. E
core +2 more sources
Control of established colon cancer xenografts using a novel humanized single chain antibody-streptococcal superantigen fusion protein targeting the 5T4 oncofetal antigen. [PDF]
PLoS ONE, 2014 Superantigens (SAgs) are microbial toxins that cross-link T cell receptors with major histocompatibility class II (MHC-II) molecules leading to the activation of large numbers of T cells.
Kelcey G Patterson +5 more
doaj +1 more source
Deimmunizing substitutions in Pseudomonas exotoxin domain III perturb antigen processing without eliminating T-cell epitopes [PDF]
Journal of Biological Chemistry, 2019 Effective adaptive immune responses depend on activation of CD4+ T cells via the presentation of antigen peptides in the context of major histocompatibility complex (MHC) class II. The structure of an antigen strongly influences its processing within the endolysosome and potentially controls the identity of peptides that are presented to T cells.
Daniel L. Moss +3 more
openaire +2 more sources
Inhibition of toxic shock by human monoclonal antibodies against staphylococcal enterotoxin B. [PDF]
PLoS ONE, 2010 BACKGROUND: Staphylococcus aureus is implicated in many opportunistic bacterial infections around the world. Rising antibiotic resistance and few alternative methods of treatment are just two looming problems associated with clinical management of S ...
Eileen A Larkin +2 more
doaj +1 more source
Transient Low T Cell Response to Streptococcal Pyrogenic Exotoxin-C in Patients with Kawasaki Disease [PDF]
Pediatric Research, 1998 Superantigens (SAs) are known to induce transient anergy followed by T cell activation. Recent reports have suggested that SAs are involved in the pathogenesis of Kawasaki disease (KD). In the present study, we investigated the peripheral T cell response to SAs by measuring proliferation and IL-2 production to determine whether the T cell anergy is ...
K, Masuda +5 more
openaire +2 more sources
The role of bacterial secretion systems in the virulence of Gram-negative airway pathogens associated with cystic fibrosis [PDF]
, 2016 Cystic fibrosis (CF) is the most common lethal inherited disorder in Caucasians. It is caused by mutation of the CF transmembrane conductance regulator (CFTR) gene.
Depluverez, Sofie +2 more
core +2 more sources