Experimental autoimmune encephalomyelitis
Biomedical Journal, 2015 Jean Kanellopoulos
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Role of nuclear factor κB in multiple sclerosis and experimental autoimmune encephalomyelitis
Neural Regeneration Research, 2018 The transcription factor nuclear factor κB (NF-κB) plays major roles in inflammatory diseases through regulation of inflammation and cell viability. Multiple sclerosis (MS) is a chronic inflammatory demyelinating and neurodegenerative disease of the ...
Yuan Yue, Sarrabeth Stone, Wensheng Lin
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Liraglutide Attenuates Disease Severity in Experimental Autoimmune Encephalomyelitis by Modulating Splenic T Helper Cell Subsets [PDF]
Brain and BehaviorObjective To investigate the therapeutic effects of liraglutide, a glucagon‐like peptide‐1 receptor agonist, on clinical progression and splenic T‐cell subsets in experimental autoimmune encephalomyelitis (EAE), a murine model of multiple sclerosis ...
Shuang Song +5 more
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B cell-specific METTL3 depletion exacerbates experimental autoimmune encephalomyelitis [PDF]
Cellular and Molecular Life SciencesN6-methyladenosine (m6A), the most prevalent RNA modification, plays a pivotal role in regulating mRNA metabolism and cellular processes such as immune responses.
Xuzhong Pei +9 more
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Experimental Autoimmune Encephalomyelitis (EAE) as a Model for Multiple Sclerosis (MS)
British Journal of Pharmacology, 2011 Bruno Gran +2 more
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Immunopathology and pathophysiology of experimental autoimmune encephalomyelitis [PDF]
, 1996 Experimental autoimmune encephalomyelitis (EAE) is an inflammatory demyelinating disease of the central nervous system (CNS), and is widely studied as an animal model of the human CNS demyelinating diseases, including multiple sclerosis (Raine, 1984). EAE can be induced by inoculation with whole CNS tissue, purified myelin basic protein (MBP) or myelin
Pender, Michael P.
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Computational Modelling of Treg Networks in Experimental Autoimmune Encephalomyelitis [PDF]
, 2011 Recent experiments have demonstrated the value of rigorously validated simulation in furthering our understanding of immunology. We seek to expand on a body of existing work at York in which we simulate the mouse disease, Experimental Autoimmune ...
Greaves, Richard
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Translational utility of experimental autoimmune encephalomyelitis: recent developments [PDF]
Journal of Inflammation Research, 2015 Andre Ortlieb Guerreiro-Cacais, Hannes Laaksonen, Sevasti Flytzani, Marie N'diaye, Tomas Olsson, Maja Jagodic Neuroimmunology Unit, Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden Abstract:
Guerreiro-Cacais AO +5 more
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Gut Microbiota-Derived Indole-3-Acetaldehyde Contributes to the Disease-Alleviating Effects of Kurarinone in Experimental Autoimmune Encephalomyelitis. [PDF]
Adv Sci (Weinh)Kurarinone ameliorates EAE via the gut microbiota‐indole‐3‐acetaldehyde‐AhR axis. Kurarinone reshapes gut microbiota and increases Akkermansia muciniphila, which promotes intestinal indole‐3‐acetaldehyde production. Indole‐3‐acetaldehyde crosses the intestinal barrier, activates AhR in CD4+ T cells, upregulates SOCS1/3, inhibits JAK2 and STAT3/4 ...
Han X +11 more
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Evaluation of methods of modeling and formation of experimental allergic encephalomyelitis [PDF]
Research Results in Pharmacology, 2022 Introduction: Experimental autoimmune (allergic) encephalomyelitis (EAE) induced by intradermal injection of homogenate of the brain, spinal cord and peripheral nerve with Freund’s stimulator, refers to a true autoimmune disease of the nervous system.
Oleksandr O. Nefodov +5 more
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