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Acute and chronic animal models for the evaluation of anti-diabetic agents
Diabetes mellitus is a potentially morbid condition with high prevalence worldwide thus being a major medical concern. Experimental induction of diabetes mellitus in animal models is essential for the advancement of our knowledge and understanding of the
Kumar Suresh +3 more
doaj +1 more source
Aim. To investigate the content of insulin-like growth factor (IGF)-1, IGF-2, and their transporter proteins IGFBP-1 and IGFBP in the liver of rats with experimental diabetes, Guerin’s carcinoma, and their combination.Materials and methods.
E. M. Frantsiyants +12 more
doaj +1 more source
Diabetes mellitus has become a serious and growing public health concern. It has high morbidity and mortality because of its complications, such as diabetic nephropathy, diabetic cardiovascular complication, diabetic neuropathy, diabetic retinopathy, and
Jin-Ming Meng +8 more
doaj +1 more source
Anti-Inflammatory Effects of Melatonin in Rats with Induced Type 2 Diabetes Mellitus
Introduction: Insulin resistance is associated with a pro-inflammatory state increasing the risk for complications in patients with type 2 diabetes mellitus (T2DM).
Hande Yapislar +6 more
doaj +1 more source
O diabetes mellitus é uma desordem endócrino-metabólica caracterizada pela hiperglicemia. O seu impacto no sistema respiratório é caracterizado por alterações funcionais e na troca gasosa.
Luiz Alberto Forgiarini Junior +4 more
doaj +1 more source
Prospective study of coffee and tea consumption in relation to risk of type 2 diabetes mellitus among men and women: The Whitehall II study [PDF]
At least fourteen cohort studies have documented all inverse association between coffee consumption and risk of type 2 diabetes. We examined the prospective association between coffee and tea consumption and the risk of type 2 diabetes mellitus among ...
Brunner, EJ +4 more
core +1 more source
Potential Biomarkers for Predicting Depression in Diabetes Mellitus
Objective: To identify the potential biomarkers for predicting depression in diabetes mellitus using support vector machine to analyze routine biochemical tests and vital signs between two groups: subjects with both diabetes mellitus and depression, and ...
Xiuli Song +9 more
doaj +1 more source
Dietary interventions to contrast the onset and progression of diabetic nephropathy. a critical survey of new data [PDF]
This article is a critical overview of recent contributions on the dietary corrections and the foods that have been claimed to delay or hinder the onset of diabetic nephropathy (DN) and its progression to end-stage renal disease.
Iacobini, Carla +3 more
core +1 more source
This paper presents the characteristics of dynamics of morphological changes of neuromuscular endings of the tongues of rats with experimentally induced streptozotocin diabetes mellitus.
M. Luchynskyi +4 more
doaj +1 more source
Adiponectin Deficiency Impairs Maternal Metabolic Adaptation to Pregnancy in Mice. [PDF]
Hypoadiponectinemia has been widely observed in patients with gestational diabetes mellitus (GDM). To investigate the causal role of hypoadiponectinemia in GDM, adiponectin gene knockout (Adipoq-/- ) and wild-type (WT) mice were crossed to produce ...
Hay, William W +6 more
core +1 more source

