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Experimental Approaches to Diabetes Mellitus

Eurasian Journal of Medicine, 2022
One of the most common health problems today, diabetes is a serious, chronic, and complex disease characterized by high blood glucose levels. Nowadays, experimental diabetes models are being developed to study existing diabetes in depth, to improve diabetes medications, or to develop new medications.
Muhammed Yayla, Damla Binnetoğlu
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Vascular Reactivity in Experimental Diabetes Mellitus [PDF]

Circulation Research, 1964
Vascular reactivity was examined in vessels of the perfused hindquarters of alloxan diabetic and control rats. A significant increase was noted in responsiveness of the diabetic animals to intra-arterial injection of epinephrine, norepinephrine, and synthetic angiotensin.
MICHAEL J. BRODY, ROBERT L. DIXON, Richard A. Shaffer   +2 more
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Insulin-like growth factors and their transporter proteins in the liver of rats with experimental diabetes, adenocarcinoma of the uterine corpus, and their combination

Бюллетень сибирской медицины, 2022
Aim. To investigate the content of insulin-like growth factor (IGF)-1, IGF-2, and their transporter proteins IGFBP-1 and IGFBP in the liver of rats with experimental diabetes, Guerin’s carcinoma, and their combination.Materials and methods.
E. M. Frantsiyants, V. A. Bandovkina, I. V. Kaplieva, E. A. Sheiko, E. I. Surikova, I. V. Neskubina, I. K. Trepitaki, Yu. A. Pogorelova, N. D. Cheryarina, L. A. Nemashkalova, I. M. Kotieva, A. V. Shaposhnikov, M. I. Morozova   +12 more
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Effects and Mechanisms of Tea for the Prevention and Management of Diabetes Mellitus and Diabetic Complications: An Updated Review

Antioxidants, 2019
Diabetes mellitus has become a serious and growing public health concern. It has high morbidity and mortality because of its complications, such as diabetic nephropathy, diabetic cardiovascular complication, diabetic neuropathy, diabetic retinopathy, and
Jin-Ming Meng, Shi-Yu Cao, Xin-Lin Wei, Ren-You Gan, Yuan-Feng Wang, Shu-Xian Cai, Xiao-Yu Xu, Pang-Zhen Zhang, Hua-Bin Li   +8 more
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Anti-Inflammatory Effects of Melatonin in Rats with Induced Type 2 Diabetes Mellitus

Life, 2022
Introduction: Insulin resistance is associated with a pro-inflammatory state increasing the risk for complications in patients with type 2 diabetes mellitus (T2DM).
Hande Yapislar, Ebru Haciosmanoglu, Turkan Sarioglu, Sevgin Degirmencioglu, Ibrahim Sogut, Michael Poteser, Cem Ekmekcioglu   +6 more
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Estresse oxidativo e alterações estruturais pulmonares no diabetes mellitus experimental Experimental diabetes mellitus: oxidative stress and changes in lung structure

Jornal Brasileiro de Pneumologia, 2009
O diabetes mellitus é uma desordem endócrino-metabólica caracterizada pela hiperglicemia. O seu impacto no sistema respiratório é caracterizado por alterações funcionais e na troca gasosa.
Luiz Alberto Forgiarini Junior, Nélson Alexandre Kretzmann, Marilene Porawski, Alexandre Simões Dias, Norma Anair Possa Marroni   +4 more
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Experimental models of diabetes mellitus [PDF]

Serbian Journal of Experimental and Clinical Research, 2011
Early studies on pancreatectomised dogs confirmed the central role of the pancreas in the homeostasis of glycemia and resulted in the discovery of insulin. Today, hundreds of different animal models are used in experimental studies of diabetes. The aim of this review is to present experimental models of type 1 and type 2 diabetes. In preparing for this
Jelena Pantic, Vladislav Volarevic, Aleksandar Djukic   +2 more
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Potential Biomarkers for Predicting Depression in Diabetes Mellitus

Frontiers in Psychiatry, 2021
Objective: To identify the potential biomarkers for predicting depression in diabetes mellitus using support vector machine to analyze routine biochemical tests and vital signs between two groups: subjects with both diabetes mellitus and depression, and ...
Xiuli Song, Xiuli Song, Qiang Zheng, Rui Zhang, Miye Wang, Wei Deng, Qiang Wang, Wanjun Guo, Tao Li, Xiaohong Ma   +9 more
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Mechanism of changes of peripheral neuromuscular endings of the tongues of rats with experimental streptozotocyn diabetes mellitus

Regulatory Mechanisms in Biosystems, 2017
This paper presents the characteristics of dynamics of morphological changes of neuromuscular endings of the tongues of rats with experimentally induced streptozotocin diabetes mellitus.
M. Luchynskyi, V. Luchinskyi, V. Shcherba, A. Demkovych, Y. Luchinska   +4 more
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Auditory Temporal Resolution in Individuals with Diabetes Mellitus Type 2

International Archives of Otorhinolaryngology, 2016
Introduction “Diabetes mellitus is a group of metabolic disorders characterized by elevated blood sugar and abnormalities in insulin secretion and action” (American Diabetes Association).
Rajkishor Mishra, Himanshu Kumar Sanju, Prawin Kumar   +2 more
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