Results 21 to 30 of about 641,645 (355)

Experimental models of diabetes mellitus [PDF]

Serbian Journal of Experimental and Clinical Research, 2011
Early studies on pancreatectomised dogs confirmed the central role of the pancreas in the homeostasis of glycemia and resulted in the discovery of insulin. Today, hundreds of different animal models are used in experimental studies of diabetes. The aim of this review is to present experimental models of type 1 and type 2 diabetes. In preparing for this
Jelena Pantic, Vladislav Volarevic, Aleksandar Djukic   +2 more
openaire   +1 more source

Acute and chronic animal models for the evaluation of anti-diabetic agents

Cardiovascular Diabetology, 2012
Diabetes mellitus is a potentially morbid condition with high prevalence worldwide thus being a major medical concern. Experimental induction of diabetes mellitus in animal models is essential for the advancement of our knowledge and understanding of the
Kumar Suresh, Singh Rajeshwar, Vasudeva Neeru, Sharma Sunil   +3 more
doaj   +1 more source

Insulin-like growth factors and their transporter proteins in the liver of rats with experimental diabetes, adenocarcinoma of the uterine corpus, and their combination

Бюллетень сибирской медицины, 2022
Aim. To investigate the content of insulin-like growth factor (IGF)-1, IGF-2, and their transporter proteins IGFBP-1 and IGFBP in the liver of rats with experimental diabetes, Guerin’s carcinoma, and their combination.Materials and methods.
E. M. Frantsiyants, V. A. Bandovkina, I. V. Kaplieva, E. A. Sheiko, E. I. Surikova, I. V. Neskubina, I. K. Trepitaki, Yu. A. Pogorelova, N. D. Cheryarina, L. A. Nemashkalova, I. M. Kotieva, A. V. Shaposhnikov, M. I. Morozova   +12 more
doaj   +1 more source

Effects and Mechanisms of Tea for the Prevention and Management of Diabetes Mellitus and Diabetic Complications: An Updated Review

Antioxidants, 2019
Diabetes mellitus has become a serious and growing public health concern. It has high morbidity and mortality because of its complications, such as diabetic nephropathy, diabetic cardiovascular complication, diabetic neuropathy, diabetic retinopathy, and
Jin-Ming Meng, Shi-Yu Cao, Xin-Lin Wei, Ren-You Gan, Yuan-Feng Wang, Shu-Xian Cai, Xiao-Yu Xu, Pang-Zhen Zhang, Hua-Bin Li   +8 more
doaj   +1 more source

Anti-Inflammatory Effects of Melatonin in Rats with Induced Type 2 Diabetes Mellitus

Life, 2022
Introduction: Insulin resistance is associated with a pro-inflammatory state increasing the risk for complications in patients with type 2 diabetes mellitus (T2DM).
Hande Yapislar, Ebru Haciosmanoglu, Turkan Sarioglu, Sevgin Degirmencioglu, Ibrahim Sogut, Michael Poteser, Cem Ekmekcioglu   +6 more
doaj   +1 more source

Estresse oxidativo e alterações estruturais pulmonares no diabetes mellitus experimental Experimental diabetes mellitus: oxidative stress and changes in lung structure

Jornal Brasileiro de Pneumologia, 2009
O diabetes mellitus é uma desordem endócrino-metabólica caracterizada pela hiperglicemia. O seu impacto no sistema respiratório é caracterizado por alterações funcionais e na troca gasosa.
Luiz Alberto Forgiarini Junior, Nélson Alexandre Kretzmann, Marilene Porawski, Alexandre Simões Dias, Norma Anair Possa Marroni   +4 more
doaj   +1 more source

Multimodal optical diagnostics of the microhaemodynamics in upper and lower limbs [PDF]

, 2019
The introduction of optical non-invasive diagnostic methods into clinical practice can substantially advance in the detection of early microcirculatory disorders in patients with different diseases.
Dremin, Viktor V., Dunaev, Andrey V., Goltsov, Alexey, Makovik, Irina N., Rafailov, Edik U., Sokolovski, Sergei G., Zherebtsov, Evgeny A., Zherebtsova, Angelina I.   +7 more
core   +4 more sources

High serum osteopontin levels are associated with prevalent fractures and worse lipid profile in post-menopausal women with type 2 diabetes [PDF]

, 2018
Purpose: Patients with type 2 diabetes (T2DM) have increased fracture risk. Osteopontin (OPN) is a protein involved in bone remodeling and inflammation.
Carnevale, V., Filardi, Tiziana, Lenzi, A., Massoud, R., Morano, S., Nieddu, L., Romagnoli, E., Russo, C., Tavaglione, F., Turinese, Irene   +9 more
core   +1 more source

Mechanism of changes of peripheral neuromuscular endings of the tongues of rats with experimental streptozotocyn diabetes mellitus

Regulatory Mechanisms in Biosystems, 2017
This paper presents the characteristics of dynamics of morphological changes of neuromuscular endings of the tongues of rats with experimentally induced streptozotocin diabetes mellitus.
M. Luchynskyi, V. Luchinskyi, V. Shcherba, A. Demkovych, Y. Luchinska   +4 more
doaj   +1 more source

Potential Biomarkers for Predicting Depression in Diabetes Mellitus

Frontiers in Psychiatry, 2021
Objective: To identify the potential biomarkers for predicting depression in diabetes mellitus using support vector machine to analyze routine biochemical tests and vital signs between two groups: subjects with both diabetes mellitus and depression, and ...
Xiuli Song, Xiuli Song, Qiang Zheng, Rui Zhang, Miye Wang, Wei Deng, Qiang Wang, Wanjun Guo, Tao Li, Xiaohong Ma   +9 more
doaj   +1 more source