Results 31 to 40 of about 7,303,354 (262)

Dynamics of endogenous intoxication in experimental diabetes mellitus

open access: yesJournal of Education, Health and Sport, 2022
Background. Nowadays, diabetes mellitus is defined as one of the global medical and social problems and shows a growing tendency. The purpose of the study was to analyze the dynamics of endogenous intoxication in experimental diabetes mellitus ...
Liubomyr Zaiats   +2 more
doaj   +1 more source

The impact of type 2 diabetes and Microalbuminuria on future cardiovascular events in patients with clinically manifest vascular disease from the Second Manifestations of ARTerial Disease (SMART) study [PDF]

open access: yes, 2008
Aims Type 2 diabetes mellitus and microalbuminuria are important risk factors for cardiovascular disease (CVD). Whether these two complications are important and independent risk factors for future CVD events in a high-risk population with clinically ...
Graaf, Y., van der   +4 more
core   +1 more source

Effect of chromium citrate on lipid composition in blood plasma of rats with experimental diabetes

open access: yesБіологічні студії, 2018
The results of studying changes of lipid composition in blood plasma of rats with alloxan-induced diabetes under the condition of consumption of chromium citrate in the concentration of 0.1 and 0.2 µg/ml of water are presented.
Iskra R.   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Sensory nerve conduction in the caudal nerves of rats with diabetes Condução nervosa sensorial no nervo caudal de ratos com diabetes experimental

open access: yesActa Cirúrgica Brasileira, 2011
PURPOSE: To investigate sensory nerve conduction of the caudal nerve in normal and diabetic rats. METHODS: Diabetes was induced in twenty 8-weeks old Wistar male rats. Twenty normal rats served as controls.
Celina Cordeiro de Carvalho   +3 more
doaj   +1 more source

Network-Level Structural Abnormalities of Cerebral Cortex in Type 1 Diabetes Mellitus [PDF]

open access: yes, 2013
Type 1 diabetes mellitus (T1DM) usually begins in childhood and adolescence and causes lifelong damage to several major organs including the brain. Despite increasing evidence of T1DM-induced structural deficits in cortical regions implicated in higher ...
Hyeonseok S Jeong   +81 more
core   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk   +10 more
wiley   +1 more source

Reduction of podocytes number in late diabetic alloxan nephropathy: prevention by glycemic control Redução do número de podócitos na fase tardia da nefropatia diabética aloxânica: prevenção pelo controle glicêmico

open access: yesActa Cirúrgica Brasileira, 2007
PURPOSE: To determine podocyte number and GBM thickness in diabetic rats either under glycemic control or without glycemic control at 6 and 12 months after diabetes induction.
Célia Sperandéo Macedo   +5 more
doaj   +1 more source

Elevated soluble CD163 in gestational diabetes mellitus : secretion from human placenta and adipose tissue [PDF]

open access: yes, 2014
Recently soluble CD163 (sCD163), a cleaved form of the macrophage receptor CD163, was identified as a macrophage-specific risk-predictor for developing Type 2 Diabetes.
Bastie, Claire C.   +30 more
core   +2 more sources

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