Results 31 to 40 of about 1,042,213 (319)

Studies In Experimental Tetanus Infection [PDF]

Journal of Medical Microbiology, 1969
Summary Evidence is given that for penicillin to prevent experimental tetanus in mice a 4-day period of treatment is satisfactory. To prevent tetanus by passive immunisation the antitoxin must remain in the circulation for 9 days. In either case Cl. tetani frequently survives at the injection site. To account for these observations it is suggested that
J W, Smith, A G, MacIver
openaire   +2 more sources

Host-pathogen interactions in Campylobacter infections: the host perspective

, 2008
Campylobacter is a major cause of acute bacterial diarrhea in humans worldwide. This study was aimed at summarizing the current understanding of host mechanisms involved in the defense against Campylobacter by evaluating data available from three sources:
Dep Infectieziekten Immunologie, Advances in Veterinary Medicine, Krogfelt, K.A., Robert J. Owen, Pelt, W., van, Karen A. Krogfelt, Shaun A. Cawthraw, Krogfelt, K., Strategic Infection Biology, Janssen, R., Wagenaar, J.A., van Pelt, W., Riny Janssen, Wilfrid van Pelt, Cawthraw, S.A., Jaap A. Wagenaar, Owen, R.J., Cawthraw, S., Owen, R.   +18 more
core   +1 more source

Separate signaling events control TCR downregulation and T cell activation in primary human T cells

Immunity, Inflammation and Disease, 2021
Introduction T‐cell antigen receptor (TCR) interaction with cognate peptide:MHC complexes trigger clustering of TCR:CD3 complexes and signal transduction.
Lieve E. H. van derDonk, Louis S. Ates, Jet van derSpek, Laura M. Tukker, Teunis B. H. Geijtenbeek, Jeroen W. J. vanHeijst   +5 more
doaj   +1 more source

Nef Obtained from Individuals with HIV-1 Vary in Their Ability to Antagonize SERINC3- and SERINC5-Mediated HIV-1 Restriction

Viruses, 2021
Nef is a multifunctional viral protein that has the ability to downregulate cell surface molecules, including CD4 and major histocompatibility complex class I (MHC-I) and, as recently shown, also members of the serine incorporator family (SERINC).
Zita Kruize, Ad C. van Nuenen, Stan W. van Wijk, Arginell F. Girigorie, Karel A. van Dort, Thijs Booiman, Neeltje A. Kootstra   +6 more
doaj   +1 more source

Naturally occurring, nonregressing canine oral papillomavirus infection: Host immunity, virus characterization, and experimental infection

, 1999
Papillomaviruses occasionally cause severe, nonregressing or recurrent infections in their human and animal hosts. The mechanisms underlying these atypical infections are not known.
Nicholls, Philip K., Klaunberg, Brenda A., Parry, N.R., Gough, Gerald W., Santos, Elmer B., Gough, G.W., Stanley, M.A., Parry, Nigel R., Stanley, Margaret A., Klaaunberg, B.A., Nicholls, P.K., Moore, Richard A., Santos, E.B., Moore, R.A.   +13 more
core   +1 more source

Different infective forms trigger distinct immune response in experimental Chagas disease. [PDF]

, 2012
Although metacyclic and blood trypomastigotes are completely functional in relation to parasite-host interaction and/or target cell invasion, they differ in the molecules present on the surface.
Olindo Assis Martins-Filho, Carneiro Cláudia Martins, Martins-Filho, Olindo Assis, Alexandre Barbosa Reis, Cláudia Martins Carneiro, Francisco Amanda Fortes, Washington Luiz Tafuri, Carvalho, Andrea Teixeira, Machado Evandro Marques de Meneses, Nogueira, Nívia Carolina, Franscisco, Amanda Fortes, Evandro Marques de Meneses Machado, Vieira, Paula Melo de Abreu, Fonseca, Kátia da Silva, Francisco, Amanda Fortes, Andrea Teixeira-Carvalho, Paula Melo de Abreu Vieira, Nogueira, N??via Carolina, Machado, Evandro Marques de Menezes, Vieira Paula Melo de Abreu, Machado, Evandro Marques de Meneses, Tafuri, Washington Luiz, Reis Alexandre Barbosa, Teixeira-Carvalho Andrea, Reis, Alexandre Barbosa, Martins-Filho Olindo Assis, Nívia Carolina Nogueira, Kátia da Silva Fonseca, Carvalho, Andréa Teixeira de, Nogueira Nívia Carolina, Amanda Fortes Francisco, Tafuri Washington Luiz, Teixeira-Carvalho, Andrea, Carneiro, Cláudia Martins, Martins Filho, Olindo Assis, Fonseca Kátia da Silva   +35 more
core   +1 more source

Small non-coding RNAs associated with viral infectious diseases of veterinary importance: potential clinical applications

Frontiers in Veterinary Science, 2016
MicroRNAs (miRNAs) represent a class of small non-coding RNA molecules that can regulate mRNAs by inducing their degradation or by blocking translation.
Mohamed eSamir, Mohamed eSamir, Frank ePessler, Frank ePessler   +3 more
doaj   +1 more source

Experimental Production of Infections in Humans

Journal of Investigative Dermatology, 1970
A reproducible experimental skin infection was a requirement before further studies on the pathogenesis of cutaneous infections could be undertaken. A variety of experimental procedures added further evidence that the skin is difficult to infect. However, a significant regional difference in susceptibility to experimental infection was demonstrated ...
Duncan, W. Christopher, McBride, Mollie E., Knox, John M.   +2 more
openaire   +2 more sources

Glyburide reduces bacterial dissemination in a mouse model of melioidosis [PDF]

, 2013
Background: Burkholderia pseudomallei infection (melioidosis) is an important cause of community-acquired Gram-negative sepsis in Northeast Thailand, where it is associated with a ,40% mortality rate despite antimicrobial chemotherapy. We showed in a
Krause, Kathrin, Ivo Steinmetz (392595), Krause Kathrin, Hanna K de Jong, de Jong, Hanna K., Wiersinga W. Joost, van der Poll Tom, Kathrin Krause (473325), de Jong Hanna K., Koh, Gavin C. K. W., Bast Antje, Katrin Breitbach (473324), Koh Gavin C. K. W., Kager, Liesbeth M., Hanna K. de Jong (304424), W. Joost Wiersinga (33895), Peacock, Sharon J., Hoogendijk, Arjan J., Gavin C K W Koh, Liesbeth M Kager, Wiersinga, W. Joost, Kager, Liesbeth M, Tom van der Poll, Koh, Gavin C K W, W Joost Wiersinga, Antje Bast, Peacock, Sharon J, Gavin C. K. W. Koh (185751), Sharon J. Peacock (35782), Tassili A. Weehuizen (473323), Steinmetz Ivo, Kager Liesbeth M., Sharon J Peacock, Jong, Hanna K. de, Liesbeth M. Kager (367131), Tom van der Poll (33907), Bast, Antje, de Jong, Hanna K, Hoogendijk, Arjan J, Steinmetz, Ivo, Breitbach, Katrin, Breitbach Katrin, Weehuizen Tassili A., Kathrin Krause, Weehuizen, Tassili A., Arjan J. Hoogendijk (473326), Antje Bast (473327), Hoogendijk Arjan J., Wiersinga, W Joost, Peacock Sharon J., Tassili A Weehuizen, van der Poll, Tom, Katrin Breitbach, Arjan J Hoogendijk, Weehuizen, Tassili A, Ivo Steinmetz   +55 more
core   +1 more source

Mutagenic Effects of Ribavirin on Hepatitis E Virus—Viral Extinction versus Selection of Fitness-Enhancing Mutations

Viruses, 2016
Hepatitis E virus (HEV), an important agent of viral hepatitis worldwide, can cause severe courses of infection in pregnant women and immunosuppressed patients. To date, HEV infections can only be treated with ribavirin (RBV).
Daniel Todt, Stephanie Walter, Richard J. P. Brown, Eike Steinmann   +3 more
doaj   +1 more source