Results 51 to 60 of about 8,357,189 (268)

Landscape of protein-protein interactions during hepatitis C virus assembly and release

Microbiology Spectrum
Assembly of infectious hepatitis C virus (HCV) particles requires multiple cellular proteins including for instance apolipoprotein E (ApoE). To describe these protein-protein interactions, we performed an affinity purification mass spectrometry screen of
Alina Matthaei, Sebastian Joecks, Annika Frauenstein, Janina Bruening, Dorothea Bankwitz, Martina Friesland, Gisa Gerold, Gabrielle Vieyres, Lars Kaderali, Felix Meissner, Thomas Pietschmann   +10 more
doaj   +1 more source

Systemic Virus Infections Differentially Modulate Cell Cycle State and Functionality of Long-Term Hematopoietic Stem Cells In Vivo

Cell Reports, 2017
Quiescent long-term hematopoietic stem cells (LT-HSCs) are efficiently activated by type I interferon (IFN-I). However, this effect remains poorly investigated in the context of IFN-I-inducing virus infections.
Christoph Hirche, Theresa Frenz, Simon F. Haas, Marius Döring, Katharina Borst, Pia-K. Tegtmeyer, Ilija Brizic, Stefan Jordan, Kirsten Keyser, Chintan Chhatbar, Eline Pronk, Shuiping Lin, Martin Messerle, Stipan Jonjic, Christine S. Falk, Andreas Trumpp, Marieke A.G. Essers, Ulrich Kalinke   +17 more
doaj   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

MORITS: An improved method to predict peptides from heterologous proteins that are recognized by the same T-cell receptor

Scientific Reports
Antigen-specific priming of T cells results in the activation of T cells that exert effector functions by interaction of their T-cell receptor (TCR) with the corresponding self-MHC molecule presenting a peptide on the surface of a target cell.
Matthias Bruhn, Moritz Spatz, Ulrich Kalinke   +2 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Mechanisms controlling anaemia in Trypanosoma congolense infected mice. [PDF]

, 2009
Trypanosoma congolense are extracellular protozoan parasites of the blood stream of artiodactyls and are one of the main constraints on cattle production in Africa.
de Angelis Martin Hrabé, Eckard Wolf, Naessens, Jan, Fuchs Helmut, Hulme, Helen, Kemp, Stephen, Alimohammadian, M.H., Wolf, Eckard, Morris Agaba, Noyes, Harry A., Hrabě de Angelis, M., de Angelis, Martin Hrabé, Agaba, M., Angelis, M.H. de, Mohammad H Alimohammadian, Martin Hrabé de Angelis, Brass Andy, Hulme Helen, Delnaz Rosh, Rathkolb, Birgit, Roshandel, Delnaz, Noyes Harry A., Rathkolb, B., Iraqi, Fuad, Fuchs, H., Hrabé de Angelis, Martin, Stephen Kemp, Jan Naessens, Wolf, E., Naessens Jan, Alimohammadian Mohammad H., Gailus-Durner, V., Gailus-Durner Valerie, Martin Hrabe ́ De Angelis, Kemp, S., Brass, Andy, Helmut Fuchs, Agaba Morris, Iraqi Fuad, Harry A. Noyes, Andy Brass, Noyes, H.A., Helen Hulme, Agaba, Morris, Kemp, Stephen J., Iraqi, F., Iraqi, F.A., Kemp Stephen, Brass, A., Harry A Noyes, Roshandel, D., Wolf Eckard, Rathkolb Birgit, Naessens, J., Delnaz Roshandel, Birgit Rathkolb, Brass, Andy; id_orcid, Alimohammadian, Mohammad H., Fuchs, Helmut, Fuad Iraqi, Wolf, Eckhard, Valerie Gailus-Durner, Hulme, H., Gailus-Durner, Valerie, Mohammad H. Alimohammadian, Roshandel Delnaz, Noyes, H.A. ; Alimohammadian, M.H. ; Agaba, M. ; Brass, A. ; Fuchs, H. ; Gailus-Durner, V. ; Hulme, H. ; Iraqi, F. ; Kemp, S. ; Rathkolb, B. ; Wolf, E. ; Hrabé de Angelis, M. ; Roshandel, D. ; Naessens, J.   +66 more
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MAVS signaling of long-lived brain-resident myeloid cells is needed during viral encephalitis to adjust the transcriptome of CNS infiltrating CD8+ T cells

Journal of Neuroinflammation
Neurotropic viruses like vesicular stomatitis virus (VSV) can infect the central nervous system (CNS) through the olfactory route. Following intranasal instillation, VSV moves along the axons of olfactory sensory neurons to the olfactory bulb.
Andreas Pavlou, Luca Ghita, Felix Mulenge, Inken Waltl, Olivia Luise Gern, Pia-Katharina Larsen, Bibiana Costa, Veronica Duran, Lena Mareike Busker, Shelly J. Robertson, Yvonne Lueder, Stephan Halle, Reinhold Förster, Sonja M. Best, Martin Stangel, Ulrich Kalinke   +15 more
doaj   +1 more source

Secreted NS1 proteins of tick-borne encephalitis virus and West Nile virus block dendritic cell activation and effector functions

Microbiology Spectrum, 2023
The flavivirus non-structural protein 1 (NS1) is secreted from infected cells into the circulation and the serum levels correlate with disease severity. The effect of secreted NS1 (sNS1) on non-infected mammalian immune cells is largely unknown. Here, we
António A. R. Camarão, Olivia Luise Gern, Felix Stegmann, Felix Mulenge, Bibiana Costa, Babak Saremi, Klaus Jung, Bernd Lepenies, Ulrich Kalinke, Imke Steffen   +9 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Cine experimental. Número 1 [PDF]

, 1944
Cine experimental (1944). Cine experimental. Número 1.
Cine experimental
core