Results 61 to 70 of about 1,042,213 (319)

Secreted NS1 proteins of tick-borne encephalitis virus and West Nile virus block dendritic cell activation and effector functions

Microbiology Spectrum, 2023
The flavivirus non-structural protein 1 (NS1) is secreted from infected cells into the circulation and the serum levels correlate with disease severity. The effect of secreted NS1 (sNS1) on non-infected mammalian immune cells is largely unknown. Here, we
António A. R. Camarão, Olivia Luise Gern, Felix Stegmann, Felix Mulenge, Bibiana Costa, Babak Saremi, Klaus Jung, Bernd Lepenies, Ulrich Kalinke, Imke Steffen   +9 more
doaj   +1 more source

Experimental infection of piglets with Cryptosporidium

Research in Veterinary Science, 1981
Piglets from five litters were doses orally with cryptosporidium originally derived from diarrhoeic calves. The piglets were either nursed by the sow, artificially reared after sucking colostrum, or weaned on to creep feed. Colostrum-fed, artificially reared piglets obtained from two litters and exposed in the first week of life developed clinical ...
S, Tzipori, E, McCartney, G H, Lawson, A C, Rowland, I, Campbell   +4 more
openaire   +2 more sources

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

MAVS signaling of long-lived brain-resident myeloid cells is needed during viral encephalitis to adjust the transcriptome of CNS infiltrating CD8+ T cells

Journal of Neuroinflammation
Neurotropic viruses like vesicular stomatitis virus (VSV) can infect the central nervous system (CNS) through the olfactory route. Following intranasal instillation, VSV moves along the axons of olfactory sensory neurons to the olfactory bulb.
Andreas Pavlou, Luca Ghita, Felix Mulenge, Inken Waltl, Olivia Luise Gern, Pia-Katharina Larsen, Bibiana Costa, Veronica Duran, Lena Mareike Busker, Shelly J. Robertson, Yvonne Lueder, Stephan Halle, Reinhold Förster, Sonja M. Best, Martin Stangel, Ulrich Kalinke   +15 more
doaj   +1 more source

Experimental Leptospirosis Infection in Chickens.

Experimental Biology and Medicine, 1948
SummaryDomestic chickens were shown to be suceptible to experimental infection with a bovine strain of leptospira, when given subcutaneously or by mouth. The infection occurs in inapparent form, as a rule.
openaire   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Quantification of airborne African Swine Fever virus after experimental infection

, 2013
Knowledge on African Swine Fever (ASF) transmission routes can be useful when designing control measures against the spread of ASF virus (ASFV). Few studies have focused on the airborne transmission route, and until now no data has been available on ...
Loeffen, W.L.A., Dep Gezondheidszorg Landbouwhuisdieren, Strategic Infection Biology, Stegeman, J.A., Carvalho Ferreira, H.C., de, Quak, S., Weesendorp, E., de Carvalho Ferreira, H.C.   +7 more
core   +1 more source

Experimental models of cryptococcosis. [PDF]

, 2011
Cryptococcosis is a life-threatening fungal disease that infects around one million people each year. Establishment and progression of disease involves a complex interplay between the fungus and a diverse range of host cell types.
May, Robin C, Sabiiti, Wilber, Robin C. May, E. Rhiannon Pursall, May, Robin; id_orcid, Sabiiti, W, May, RC, Pursall, ER, Wilber Sabiiti, Pursall, E Rhiannon   +9 more
core   +1 more source

Experimental Investigations in the Infection of Wounds [PDF]

Annals of Surgery, 1894
n ...
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source