Results 241 to 250 of about 2,221,895 (307)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Multi-scale evidence chain: Linking environmental BPA exposure to ovarian cancer through integrated omics and experimental models. [PDF]

Transl Oncol
Luo Y, Mo S, Song P, Meng K, Zhou J, Zou Y.   +5 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Experimental Models to Investigate Viral and Cellular Dynamics in Respiratory Viral Co-Infections. [PDF]

Microorganisms
Yazici O, Vanetti C, Clerici M, Biasin M.   +3 more
europepmc   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

iPSC-Derived Endothelial Cells as Experimental Models for Predictive and Personalized Strategies in Cardiovascular and Cerebrovascular Disease. [PDF]

Int J Mol Sci
Fontanelli L, Castronovo A, Ferri C, Vozzi F, Recchia FA, Borghini A.   +5 more
europepmc   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

The Relevance of Experimental Models in Assessing the Impact of Oxidative Stress on Intestinal Pathology. [PDF]

J Clin Med
Pavel CD, Gales C, Pavel IA, Zamfir CL.
europepmc   +1 more source

Experimental models of epilepsy: A comprehensive review of mechanisms, translational relevance, and future directions. [PDF]

Vet World
Jiji PJ, Rai R, Kumar NA, Blossom V, Pai MM, Rai AR, Vadgaonkar R, Nayak SD.   +7 more
europepmc   +1 more source

Correction: Effect of PM2.5 exposure on susceptibility to allergic asthma in elderly rats treated with allergens

Scientific Reports
Lianlian Zhao, Xiaolin Ding, Li Zhou, Chenchen Song, Taisheng Kang, Yanfeng Xu, Yunpeng Liu, Yunlin Han, Wenjie Zhao, Boxiang Zhang, Dan Xu, Jianguo Guo   +11 more
doaj   +1 more source