Results 251 to 260 of about 14,115,327 (313)

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Berberine Toxicity Profile in Experimental Models as a Basis for Assessing Its Biological Safety. [PDF]

Molecules
Karczmarzyk A, Wojcieszyńska D, Nowak A, Smułek W, Guzik U.   +4 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Hydrogel-based experimental models of the gastrointestinal tract. [PDF]

Microbiome
Sieders M, Candry P, El Aidy S.
europepmc   +1 more source

Induced Pluripotent Stem Cell-Based Platforms for Cardiac-Related Pain Research: Molecular Mechanisms, Experimental Models, and Therapeutic Applications. [PDF]

Int J Mol Sci
Liao B, Lee AK, Gu Z, Meng F, Wu J, Yang J, Wong SS.   +6 more
europepmc   +1 more source

Mechanisms of Phthalate-Induced Accelerated Ovarian Aging in Experimental Models. [PDF]

Curr Environ Health Rep
Safar AM, Flaws JA.
europepmc   +1 more source

Correction: Effect of PM2.5 exposure on susceptibility to allergic asthma in elderly rats treated with allergens

Scientific Reports
Lianlian Zhao, Xiaolin Ding, Li Zhou, Chenchen Song, Taisheng Kang, Yanfeng Xu, Yunpeng Liu, Yunlin Han, Wenjie Zhao, Boxiang Zhang, Dan Xu, Jianguo Guo   +11 more
doaj   +1 more source

Experimental Models and Translational Strategies in Neuroprotective Drug Development with Emphasis on Alzheimer's Disease. [PDF]

Molecules
Niziński P, Szalast K, Makuch-Kocka A, Paruch-Nosek K, Ciechanowska M, Plech T.   +5 more
europepmc   +1 more source

Fetal and neonatal brain protection at term-The role of translational experimental models. [PDF]

Acta Obstet Gynecol Scand
Lantto J, Kiviranta P, Voipio J.
europepmc   +1 more source

Going wild: prioritizing experimental models of rodent-borne viruses to decode zoonotic spillover and pandemic risk. [PDF]

J Virol
Honce R, Botten J.
europepmc   +1 more source