Results 261 to 270 of about 14,115,327 (313)

Explicit Modelling of Model Debugging and Experimentation.

, 2014
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Epileptogenesis in Experimental Models

Epilepsia, 2007
Summary:  Epileptogenesis refers to a phenomenon in which the brain undergoes molecular and cellular alterations after a brain‐damaging insult, which increase its excitability and eventually lead to the occurrence of recurrent spontaneous seizures. Common epileptogenic factors include traumatic brain injury (TBI), stroke, and cerebral infections.
Pitkänen, Asla, Kharatishvili, Irina, Karhunen, Heli, Lukasiuk, Katarzyna, Immonen, Riikka, Nairismägi, Jaak, Gröhn, Olli, Nissinen, Jari   +7 more
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Experimental Models of Dystonia

2011
Dystonia is a disabling movement disorder characterized by involuntary, sustained muscle contractions, with repetitive twisting movements and abnormal postures. It is clinically classified as primary, either sporadic or genetic, or secondary, following focal brain lesions. The recent past has witnessed remarkable progress in finding genes for dystonia.
Tassone, A, SCIAMANNA, GIUSEPPE, Bonsi, P, MARTELLA, GIUSEPPINA, PISANI, ANTONIO   +4 more
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Experimental Models Of Ossiculoplasty

Otolaryngologic Clinics of North America, 1994
Measurement of the acoustic properties of middle ear prostheses in an appropriate model prior to insertion in humans should be part of the routine of the prosthesis development and testing process, but it is not. This article describes a human temporal bone model suitable for such testing and discusses the results of several commonly used prostheses ...
R L, Goode, S, Nishihara
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Experimental models of sarcoidosis

Current Opinion in Pulmonary Medicine, 2016
Sarcoidosis is a disease caused by a complex combination of genetic susceptibility, immune networks and infectious and/or environmental agents. The onset and phenotypic variability of sarcoidosis remain poorly elucidated, not only due to the lack of clearly identified causes, but also because it is widely considered that no reliable model of this ...
Florence, Jeny, Yves, Pacheco, Valerie, Besnard, Dominique, Valeyre, Jean-François, Bernaudin   +4 more
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Experimental models in microsurgery

Microsurgery, 1998
The development of experimental microsurgery can be considered the natural evolution of a diffuse need to increase precision in many fields of surgery. Microsurgery accelerated the possibility of deepening many unclear aspects of pathophysiology, using miniaturized and reproducible experimental models. We report briefly on the fundamental principles of
DI CATALDO, Antonio, LA GRECA, Gaetano, Rodolico M, Candiano C, LI DESTRI, Giovanni, Puleo S.   +5 more
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Experimental models in rhinitis

Clinical & Experimental Allergy, 1999
Nasal challenge with allergen or mediators is a useful model to understand the pathophysiology of allergic rhinitis. Some mechanisms have thereby been clearly clarified. Different methods have been proposed to mimic the natural allergen exposure and to measure the clinical and biological responses. Nasal challenges can also be used in clinical practice,
P, Demoly, A, Campbell, B, Lebel, J, Bousquet   +3 more
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Experimental Models in Nanotoxicology

2011
The aim of toxicology is to characterise the potentially harmful effects of solid, liquid, or gaseous substances for humans. Having evaluated the hazards, and given the level of exposure to the substance, we can then assess the risks.
Baeza-Squiban, Armelle, Lacroix, Ghislaine, Bois, Frédéric Y.   +2 more
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Cachexia in experimental models

Nutrition, 1999
Cachexia refers to a state of severe malnutrition characterized by anorexia, weight loss, and muscle wasting. Although it is most commonly considered in the context of cancer, it may occur as a consequence of a variety of chronic diseases. Cachexia appears to differ from "semistarvation" in that there is evidence of metabolic changes that are different
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Experimental Model for Scleritis

Archives of Ophthalmology, 1979
Rabbits were sensitized over a prolonged period to ovalbumin by intradermal injection. Ovalbumin was then injected into the limbus of the eye. A corneoscleral lesion, similar to necrotizing scleritis in humans, was produced. The clinical progression of the lesion is described and its histologic appearance discussed in relation to the human disease.
R M, Hembry, J, Playfair, P G, Watson, J T, Dingle   +3 more
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