Results 91 to 100 of about 5,529,456 (280)
The FOUCAULTian governmentality approach, in relying on a teleology—the ultimate purpose of human endeavour is the quest for ever-growing human reason, a reason that is the universal basis of moral judgements, especially moral judgements about political ...
Gary Wickham, Gavin Kendall
doaj
A Gravitational Explanation for Quantum Mechanics [PDF]
It is shown that certain structures in classical General Relativity can give rise to non-classical logic, normally associated with Quantum Mechanics. A 4-geon model of an elementary particle is proposed which is asymptotically flat, particle-like and has
Hadley, Mark J.
core +2 more sources
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Arithmetic, Set Theory, Reduction and Explanation [PDF]
Philosophers of science since Nagel have been interested in the links between intertheoretic reduction and explanation, understanding and other forms of epistemic progress.
D’Alessandro, William
core
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Causal Factors, Causal Inference, Causal Explanation [PDF]
There are two concepts of causes, property causation and token causation. The principle I want to discuss describes an epistemological connection between the two concepts, which I call the Connecting Principle.
Papineau, David, Sober, Elliott
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
The Structure of Sensorimotor Explanation [PDF]
The sensorimotor theory of vision and visual consciousness is often described as a radical alternative to the computational and connectionist orthodoxy in the study of visual perception.
Vernazzani, Alfredo
core +1 more source

