Results 101 to 110 of about 5,529,456 (280)
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Interpretation, Explanation and Theories of Meaning
SociologicaWe use the work of Clifford Geertz to examine long-standing questions about the relationship between interpretation and explanation. We extract from Geertz’s work explanatory theories of what we are calling meaning and meaningfulness.
Ann Swidler, Ronald L. Jepperson
doaj +1 more source
Skepticism, Externalism, and Inference to the Best Explanation [PDF]
, 2008 This paper focuses on a combination of the antiskeptical strategies offered by semantic externalism and the inference to the best explanation. I argue that the most difficult problems of the two strategies can be solved, if the strategies are combined ...
Briesen, Jochen
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
IEEE Access, 2019 Recommender Systems are widely adopted in nowadays services such as e-commerce websites, multimedia streaming platforms, and many others. They help users to find what they are looking for by suggesting relevant items leveraging their past preferences ...
Vito Bellini +3 more
doaj +1 more source
Explanation of the Helium-3 problem
, 2011 One of the tests of nucleosynthesis theory is the $^3$He abundance in the Galaxy. $^3$He$^+$ is observed through its 3.46 cm hyperfine level in Hii regions and the $^3$He/H ratio compares well with theory.
Nieuwenhuizen, Theo M.
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
A Star is Born? The Authors, Principles and Objectives of Analytical Sociology
Papers, 2006 This article presents the main features and objectives of the so-called «social mechanisms based explanation» or «analytical sociology». This perspective has gained quite considerable attention in contemporary debate, both for its theoretical novelty as ...
Filippo Barbera
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Explanation of Reference System, pp. xlix-li [PDF]
, 1944 The Catherwood Library and ILR School at Cornell are pleased to again make available an extremely important index of major labor union publications, long out of print. It is Lloyd G. Reynolds and Charles C.
Killingsworth, Charles C +1 more
core +1 more source