Results 131 to 140 of about 1,959,540 (314)
Some Remarks On Statistics And Scientific
and to enlarge such explanations with predictions of what future events will be seen next. What distinguishes scientific from other methods is explanation and prediction by rule, characterized by its explicit and public character.
Marlos Viana +2 more
core
The Crux of Crucial Experiments: Duhem’s Problems and Inference to the Best Explanation [PDF]
Going back at least to Duhem, there is a tradition of thinking that crucial experiments are impossible in science. I analyse Duhem’s arguments and show that they are based on the excessively strong assumption that only deductive reasoning is permissible ...
Weber, Marcel
core
Scientific explanation and the troubles with Causal explanations in physics
Fifty years ago, Carl Gustav Hempel published his famous book Aspects of Scientific Explanation. Since then the number of publications on this subject has grown exponentially. An occasion like this deserves to be commemorated. In this article I offer a modest tribute to this great methodologist of science.
openaire +4 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Happiness Prediction With Domain Knowledge Integration and Explanation Consistency
Happiness prediction based on large-scale online data and machine learning models is an emerging research topic that underpins a range of issues, from personal growth to social stability.
Li, Lin +4 more
core +1 more source
Qualitative Theory and Chemical Explanation [PDF]
Roald Hoffmann and other theorists claim that we we ought to use highly idealized chemical models (``qualitative models'') in order to increase our understanding of chemical phenomena, even though other models are available which make more highly ...
Weisberg, Michael
core
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
The study of the variation and explanation of Tw-DRGs V3.0
[[abstract]]The purpose of this study was to assess the adequacy of the third version of Tw-DRGs. The adequacy was determined by calculating the coefficient variation (CV) and the coefficient of determination (R2) of the charges and lengths of stay (LOS).
TASI HUI FANG
core
Scientific Reasoning Is Material Inference: Combining Confirmation, Discovery, and Explanation [PDF]
Whereas an inference (deductive as well as inductive) is usually viewed as being valid in virtue of its argument form, the present paper argues that scientific reasoning is material inference, i.e., justified in virtue of its content.
Brigandt, Ingo
core
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source

