Results 161 to 170 of about 1,577,647 (265)

Guidance for protocol content and reporting of dog-assisted interventions in randomised controlled trials: explanation and elaboration of the SPIRIT 2025 and CONSORT 2025 extensions. [PDF]

BMC Med Res Methodol
Shoesmith E, Ratschen E, Riga E, Mills DS, Gibsone S, McMillan D, Wu Q, Clarke C, Sprange K, Meints K, Gee NR, Nieforth LO, Dollion N, Fine A, Hall SS.   +14 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

A systematic evaluation of explainable AI methods for high-dimensional transcriptome-based cancer survival prediction. [PDF]

Front Physiol
Zuo Y, Yang S, Zhao W.
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Scientific Explanation

, 2013
Weber, Erik, Van Bouwel, Jeroen, De Vreese, Leen   +2 more
openaire   +1 more source

Enhancing Dental Students' Communication Skills Through Peer Role-Play and AI-Assisted Feedback in Periodontal Preclinical Course. [PDF]

J Dent Educ
Li MH, Chen CY, Park S, Wang CW.
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Syringomyelia and hydrocephalus following tuberculosis are not necessarily caused by mild Chiari I malformation. [PDF]

Korean J Fam Med
Zarrouk S, Finsterer J.
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Explainable AI needs formalization. [PDF]

NPJ Artif Intell
Haufe S, Wilming R, Clark B, Zhumagambetov R, Boubekki A, Martin J, Panknin D.   +6 more
europepmc   +1 more source