Results 171 to 180 of about 1,630,412 (217)

Statement of Retraction: N⁶-methyladenosine (m⁶A) reader IGF2BP2 promotes gastric cancer progression via targeting SIRT1. [PDF]

Bioengineered
europepmc   +1 more source

Beyond diagnosis in general practice: Predictive processing, a novel framework for persistent physical symptoms. [PDF]

Eur J Gen Pract
van Boven K, Lucassen P, Hartman TCO, Van den Bergh O.   +3 more
europepmc   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Clinically Interpretable Deep Learning for Differentiating Vitiligo and Postinflammatory Hypopigmentation: Diagnostic Accuracy Study. [PDF]

JMIR Med Inform
Alzu'bi AA, Al Khateeb S, Elzaghmouri BM, Alshiyab DM, Abu Alasal S, Zhou L.   +5 more
europepmc   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Dual attitudes toward doctors: the role of shared decision-making and empathy in frustrated medical treatment in a randomized trial. [PDF]

Front Public Health
Ying L, Chen Y, Wang X, Huang J, Yan J, Song J, Zhou Q.   +6 more
europepmc   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Explainable Artificial Intelligence for Early Diabetic Kidney Disease Risk Profiling in Type 2 Diabetes: Translational Readiness and Clinical Boundaries. [PDF]

Diabetes Metab Syndr Obes
Wu T, Cai W, Guan Z, Li Z.
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Prescribing a dose of transparency: a qualitative evaluation of AI explanations with cardiovascular healthcare professionals. [PDF]

Front Artif Intell
Haas S, Högemann M, Thomas O.
europepmc   +1 more source