Results 181 to 190 of about 5,529,456 (280)

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Rejected by an AI? Comparing job applicants' fairness perceptions of artificial intelligence and humans in personnel selection. [PDF]

Front Artif Intell
Malin C, Fleiß J, Ortlieb R, Thalmann S.   +3 more
europepmc   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source

An unsupervised XAI framework for dementia detection with context enrichment. [PDF]

Sci Rep
Singh D, Brima Y, Levin F, Becker M, Hiller B, Hermann A, Villar-Munoz I, Beichert L, Bernhardt A, Buerger K, Butryn M, Dechent P, Düzel E, Ewers M, Fliessbach K, Freiesleben SD, Glanz W, Hetzer S, Janowitz D, Görß D, Kilimann I, Kimmich O, Laske C, Levin J, Lohse A, Luesebrink F, Munk M, Perneczky R, Peters O, Preis L, Priller J, Prudlo J, Prychynenko D, Rauchmann BS, Rostamzadeh A, Roy-Kluth N, Scheffler K, Schneider A, Droste Zu Senden L, Schott BH, Spottke A, Synofzik M, Wiltfang J, Jessen F, Weber MA, Teipel SJ, Dyrba M.   +46 more
europepmc   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Performance Analysis of Explainable Deep Learning-Based Intrusion Detection Systems for IoT Networks: A Systematic Review. [PDF]

Sensors (Basel)
Ogunseyi TB, Thiyagarajan G, He H, Bist V, Du Z.   +4 more
europepmc   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

[Retracted] miR‑367 enhances the proliferation and invasion of cutaneous malignant melanoma by regulating phosphatase and tensin homolog expression. [PDF]

Mol Med Rep
Long J, Luo J, Yin X.
europepmc   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Comparative Evidence-Based Model Choice: A Sketch of a Theory. [PDF]

Entropy (Basel)
Bandyopadhyay PS, Shetty S, Brittan G.
europepmc   +1 more source