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Attention is not not Explanation [PDF]

Proceedings of the 2019 Conference on Empirical Methods in Natural Language Processing and the 9th International Joint Conference on Natural Language Processing (EMNLP-IJCNLP), 2019
Attention mechanisms play a central role in NLP systems, especially within recurrent neural network (RNN) models. Recently, there has been increasing interest in whether or not the intermediate representations offered by these modules may be used to explain the reasoning for a model's prediction, and consequently reach insights regarding the model's ...
Sarah Wiegreffe, Yuval Pinter
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

alisonpease/Explanation-Data: Mini-Polymath1-4_Explanation_Data

, 2018
<p>This is the annotated data for our explanation study into mini-Polymath conversations 1-4.</p ...
alisonpease
core   +1 more source

Soul as Explanatory Cause of Life in Aristotle: Scientific Knowledge simpliciter (ἁπλῶς) through Coextensive Universal Demonstrations and Context Restriction as a Solution to a Core-Dependent Homonymy from DA II.1-4

Archai: Revista de Estudos sobre as Origens do Pensamento Ocidental
The main purpose of this paper is to show, based on Aristotle’s theory of scientific demonstration, how soul plays the role of explanatory cause of life in De Anima (DA) II.1-4.
Ahmad Suhail Farhat
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Determinants of Judgments of Explanatory Power: Credibility, Generality, and Statistical Relevance

Frontiers in Psychology, 2017
Explanation is a central concept in human psychology. Drawing upon philosophical theories of explanation, psychologists have recently begun to examine the relationship between explanation, probability and causality.
Matteo Colombo, Leandra Bucher, Jan Sprenger   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Explanation in human-agent teamwork

, 2012
There are several applications in which humans and agents jointly perform a task. If the task involves interdependence among the team members, coordination is required to achieve good team performance.
Bosch, K. van den, Meyer, J.J.C., Jeffrey M. Bradshaw, Johnson, M., Maaike Harbers, Paul Feltovich, Harbers, M., Karel van den Bosch, Feltovich, P., Bradshaw, J.M., Matthew Johnson, John-Jules Meyer   +11 more
core   +1 more source

What Does It Mean to Explain?

Exchanges
We summarise and reflect on the symposium ‘Let me explain: Reason-giving across disciplines’, held at the University of Warwick's Institute of Advanced Study in June 2024. The event brought together scholars from four faculties to discuss the concept of
Yvette Yitong Wang, Simon Gansinger
doaj   +1 more source