Results 91 to 100 of about 40,773 (278)
N-terminal Tail Export from the Mitochondrial Matrix [PDF]
Journal of Biological Chemistry, 1999 Elena E. Rojo +3 more
openaire +1 more source
Advanced Science, EarlyView.This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma +16 more
wiley +1 more source
The BnTFL1‐BnJAM3‐BnSWEETs Module Orchestrates Seed Storage Reserve Accumulation in Brassica napus
Advanced Science, EarlyView.BnaC03.TFL1 and BnaA01.JAM3 form a complex that facilitates the transport of soluble sugars from the seed coat to the embryo by directly activating the expression of BnSWEETs. Furthermore, BnaC03.TFL1 and BnaA01.JAM3 work cooperatively to promote soluble sugar and oil production while suppressing protein deposition.
Jianjun Wang +8 more
wiley +1 more source
Managing waste exports when closure risks are endogenous [PDF]
This paper provides a rationale for taxing waste exports when closure risks are endogenous in that they depend on the importing country's accumulated stock of waste.
Michaelis, Peter, Stähler, Frank
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Advanced Science, EarlyView.This research identifies DTX3L as a critical tumor suppressor that inhibits epithelial‐mesenchymal transition (EMT), invasion and metastasis in gastric cancer. By functioning as an E3 ubiquitin ligase, DTX3L targets the master EMT regulator SNAI1 for GSK‐3β‐dependent proteasomal degradation.
Yang Chen +7 more
wiley +1 more source
Explaining regionalization of trade in Asia Pacific: A transaction cost approach [PDF]
Recent investigations on the regional distribution of trade flows in the Asia Pacific area suggest that some countries have developed strong bilateral trade links, while others obviously tend to be more closely linked towards trading partners outside the
Amelung, Torsten
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The specialized terminal of vehicles in brazilian exports: the case of terminal Santos Brazil
, 2019 This article presents a descriptive bibliographic study of Brazilian export vehicles, as a specializedterminal, aiming to show the structure and capacity of the terminal, and the logistical process for loading and unloading operation of the ship, and the necessary documentation for the release of vehicles on export and import, was presented also a ...
Farias, Stephany, Raymundo, Julio Cesar
openaire +1 more source
Advanced Science, EarlyView.ABSTRACT Engineered ascorbate peroxidase APEX2 has been widely used for spatially restricted profiling of subcellular biomolecules, but its catalytic efficiency toward newly developed probes such as biotin‐aniline (Btn‐An) remains suboptimal. To overcome this limitation, we performed yeast surface display‐based directed evolution to enhance APEX2 ...
Gang Wang, Yi Li, Peiyuan Meng, Peng Zou
wiley +1 more source
Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis
Angewandte Chemie, EarlyView.Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley +2 more sources
GROWTH POLES AND NATIONAL COMPETITIVNESS [PDF]
The mainstream approach of international trade (Smith, Ricardo, Heckscher- Ohlin etc.) envisages the national economy as an heterogenous space of ressources and factors and the competitivness depends upon right chosen industrial and trade policies.
BELU Mihaela, POPA Ioan
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