Results 111 to 120 of about 2,584 (204)

Bisphenol S Induces Lipid Metabolism Disorders in HepG2 and SK-Hep-1 Cells via Oxidative Stress

Toxics
Bisphenol S (BPS) is a typical endocrine disruptor associated with obesity. To observe BPS effects on lipid metabolism in HepG2 and SK-Hep-1 human HCC cells, a CCK-8 assay was used to assess cell proliferation in response to BPS, and the optimal ...
Kai-Xing Lin, Zi-Yao Wu, Mei-Lin Qin, Huai-Cai Zeng   +3 more
doaj   +1 more source

MetaboAnalyst 6.0: towards a unified platform for metabolomics data processing, analysis and interpretation. [PDF]

We introduce MetaboAnalyst version 6.0 as a unified platform for processing, analyzing, and interpreting data from targeted as well as untargeted metabolomics studies using liquid chromatography - mass spectrometry (LC-MS).
Hui, Fiona, Li, Shuzhao, Lu, Yao, MacDonald, Patrick E, Pang, Zhiqiang, Spigelman, Aliya F, Viau, Charles, Wishart, David S, Xia, Jianguo, Xu, Lei, Zhou, Guangyan   +10 more
core   +2 more sources

The role and mechanism of miR-425–3p regulating neuronal pyroptosis -mediated inorganic arsenic-induced generalized anxiety disorder

Ecotoxicology and Environmental Safety
Pyroptosis plays a critical role in the pathogenesis of mental disorders. However, its specific role and mechanism in arsenic (As)-induced generalized anxiety disorder (GAD) remain elusive.
Wei-Xing Lei, Lei Zhang, Jin-Li Chen, Gao-Hui Zheng, Lin-Nan Guo, Tao Jiang, Zi-yue Yin, Ming-Ying, Qi-ming Yu, Na Wang   +9 more
doaj   +1 more source

The Human Exposome

Journal of the American College of Cardiology, 2019
(Uploaded by Plazi for the Bat Literature Project) No abstract provided.
openaire   +1 more source

Functional genetic variants and susceptibility and prediction of gestational diabetes mellitus

Scientific Reports
The aetiological mechanism of gestational diabetes mellitus (GDM) has still not been fully understood. The aim of this study was to explore the associations between functional genetic variants screened from a genome-wide association study (GWAS) and GDM ...
Gongchen Huang, Yan Sun, Ruiqi Li, Lei Mo, Qiulian Liang, Xiangyuan Yu   +5 more
doaj   +1 more source

Associations between the METS-IR index and cognitive function in community-dwelling Chinese middle-aged and older adult individuals: a cross-sectional study

Frontiers in Public Health
ObjectiveThe relationship between insulin resistance and cognitive function has long been a subject of interest, but the association between the metabolic syndrome-insulin resistance (METS-IR) index and cognitive impairment remains unclear.MethodsWe ...
Nian Jiang, Nian Jiang, Chenlu Ma, Chenlu Ma, Zhenning Feng, Zhenning Feng, Yongjun Tang, Yongjun Tang, Xiaolong Chen, Xiaolong Chen, Yingxu He, Yingxu He, Weiyi Pang, Weiyi Pang, Weiyi Pang   +14 more
doaj   +1 more source

Only one health, and so many omics [PDF]

, 2015

core   +1 more source

Commentary: Data Processing Thresholds for Abundance and Sparsity and Missed Biological Insights in an Untargeted Chemical Analysis of Blood Specimens for Exposomics

Frontiers in Public Health, 2022
Pekka Keski-Rahkonen, Oliver Robinson, Rossella Alfano, Rossella Alfano, Michelle Plusquin, Augustin Scalbert   +5 more
doaj   +1 more source

Neurotoxicity of manganese via ferroptosis induced by redox imbalance and iron overload

Ecotoxicology and Environmental Safety
Manganese (Mn) is an essential trace element for maintaining bodily functions. Excessive exposure to Mn can pose serious health risks to humans and animals, particularly to the nervous system.
Changyong Wang, Hongyan Zhao, Yaoyang Liu, Minghai Qu, Shanyu Lv, Guoguo He, Hongshuo Liang, Kemiao Chen, Lin Yang, Yonghua He, Chaoyan Ou   +10 more
doaj   +1 more source

Exposome-wide Association Study for Metabolic Syndrome

Frontiers in Genetics, 2021
Peng Gao, Michael Snyder
doaj   +1 more source