Results 101 to 110 of about 1,965 (197)

Microextraction Technologies as Exposomic Sensors for On-Site Environmental Air Monitoring of Volatile Organic Compounds: A Review of Commercially Available Technologies

Molecules
Microextraction Technologies (METs) have emerged as pivotal exposomic sensors for the on-site monitoring of Volatile Organic Compounds (VOCs) in ambient air.
Stefano Dugheri, Nicola Mucci, Ilaria Rapi, Giovanni Cappelli, Ettore Guerriero, Fabio Cioni, Domenico Cipriano, Ivana Stanimirova, Veronica Traversini, Antonio Baldassarre, Riccardo Gori   +10 more
doaj   +1 more source

Development of LC-MS/MS Database Based on 250 Potentially Highly Neuroactive Compounds and Their Metabolites

Metabolites
Background: Environmental chemicals are hypothesized to contribute to the development of neurodevelopmental disorders; however, only a fraction of the thousands of chemicals in common commercial use have validated assays.
Taylor Teitelbaum, Haoduo Zhao, Lauren E. Koval, Yun-Chung Hsiao, Chih-Wei Liu, Julia E. Rager, Stephanie M. Engel, Kun Lu   +7 more
doaj   +1 more source

The exposome and health

Science, 2020
Despite extensive evidence showing that exposure to specific chemicals can lead to disease, current research approaches and regulatory policies fail to address the chemical complexity of our world. To safeguard current and future generations from the increasing number of chemicals polluting our environment, a systematic and agnostic approach is needed.
Vermeulen, Roel, Schymanski, Emma L, Barabási, Albert-László, Miller, Gary W   +3 more
openaire   +1 more source

An evolutionary perspective for the exposome

Exposome
Abstract The exposome was proposed following the realization that most human diseases have an environmental rather than a genetic (hereditary) origin. Non-communicable diseases are, in fact, the consequence of multiple exposures that activate a sequence of stages in a multistage process that already starts in early life.
Paolo Vineis, Sonia Dagnino
openaire   +2 more sources

The hepatocellular model of fatty liver disease: from current imaging diagnostics to innovative proteomics technologies

Frontiers in Medicine
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is a prevalent chronic liver condition characterized by lipid accumulation and inflammation, often progressing to severe liver damage. We aim to review the pathophysiology, diagnostics, and
Renee Hernandez, Natasha S. Garcia-Rodriguez, Marco A. Arriaga, Ricardo Perez, Auwal A. Bala, Ana C. Leandro, Ana C. Leandro, Vince P. Diego, Vince P. Diego, Marcio Almeida, Marcio Almeida, Jason G. Parsons, Eron G. Manusov, Jacob A. Galan, Jacob A. Galan   +14 more
doaj   +1 more source

Measurement of China’s public health level: compilation and research of an index

BMC Public Health
Background With the development of the economy, public health has become increasingly important. Therefore, it is important to establish a comprehensive and scientific the public health level index (PHL) system to measure public health level as a ...
Zhengqi Wei, Keke Wei, Yan Li, Lijie Nie, Yizhuang Zhou   +4 more
doaj   +1 more source

The exposome in practice: Design of the EXPOsOMICS project [PDF]

EXPOsOMICS is a European Union funded project that aims to develop a novel approach to the assessment of exposure to high priority environmental pollutants, by characterizing the external and the internal ...
Kleinjans, Jos C. S., Vineis, Paolo, EXPOsOMICS Consortium, Nieuwenhuijsen, Mark J., Kogevinas, Manolis, Wild, Christopher P., Vermeulen, Roel, Phillips, David H., Probst-Hensch, Nicole M., Gmuender, Hans, Gulliver, John, Kyrtopoulos, Soterios, Chadeau-Hyam, Marc, Scalbert, Augustin, Herceg, Zdenko   +14 more
core  

Librarian: An Open-Access Web Application for High-Resolution Mass Spectral Library Assembly

Metabolites
Background: Confident chemical annotation in nontarget small-molecule mass spectrometry critically depends on the availability of high-quality tandem mass spectral (MS2) reference libraries.
Jacob Ahlberg Weidenfors, Bénilde Bonnefille, Stefano Papazian   +2 more
doaj   +1 more source

Exposome Shiny: a Toolbox for exposome data analysis

, 2021
The exposome is a collection of environmental factors, such as air pollution, stress and diet, to which an individual is exposed and which can have an effect on health. There are several large projects aimed at the study of the exposome and their impact on human traits such as HELIX, EXPOsOMICS and Hercules among others.
openaire   +1 more source

Identification of environmental etiologies of neurodevelopmental disorders in children

生物医学转化
Neurodevelopmental disorders (NDDs) are a group of chronic developmental brain dysfunctions caused by various genetic or acquired factors, characterized by high disability rates and a lack of effective treatments.
Li Yuanyuan
doaj   +1 more source