Results 91 to 100 of about 2,584 (204)

The Impact of the Metal Mixture Inflammation Index on All‐Cause Mortality in Patients With Cardiovascular‐Kidney‐Metabolic Syndrome Stages 0–3: A Study Based on NHANES 1999–2010

Cardiovascular Therapeutics, Volume 2026, Issue 1, 2026.
Objective Environmental exposure to metals is recognized as a significant trigger of chronic inflammation and various systemic diseases, with inflammatory processes playing a central role in the development and progression of CKM syndrome. The MMII, which integrates multiple metal exposures and inflammatory responses, has demonstrated sensitivity in ...
Wenlong Ding, Fachao Shi, Lei Fang, Qin Cui, Caoyang Fang, Abhishesh Mehata   +5 more
wiley   +1 more source

Personalizing medicine in silico and in socio [PDF]

, 2016
Proponents of the emerging field of P4 medicine (defined as personalized, predictive, preventive and participatory) argue that computational integration and analysis of patient-specific “big data” will revolutionize our health care systems, in particular
Green, Sara, Vogt, Henrik
core  

Multi‐Omics‐Driven Adaptive Management of Biological Invasions: Toward a Proactive, Predictive, and Integrative Framework

Biological Diversity, Volume 2, Issue 4, Page 163-192, December 2025.
A proactive, predictive, and integrative framework that integrates multi‐omics innovations with ecological modeling and big data analytics to guide adaptive interventions and governance in invasive species management. By integrating multi‐omics insights with advanced ecological modeling, remote sensing, artificial intelligence, and cross‐disciplinary ...
Aibin Zhan
wiley   +1 more source

Integrating Microbiomes for Regenerative Food Systems: Recent Insights, Implementations, and Emerging Trends

Food Science &Nutrition, Volume 13, Issue 12, December 2025.
This review explores how the specific understanding of native microbiome dynamics can aid in advancing agricultural practices and food safety. It also reviews recent advances in microbiome‐targeted technologies, including personalized nutrition, functional foods, and engineered approaches.
Muhammad Tayyab Arshad, Sammra Maqsood, Md. Sakhawot Hossain, Farhang Hameed Awlqadr, Abdul Rauf, Iffat Ullah, Ali Ikram, Ayesha Bibi, Sayeed Mukhtar, Muhammed Adem Abdullahi   +9 more
wiley   +1 more source

Puerarin Attenuates the Cytotoxicity Effects of Bisphenol S in HT22 Cells by Regulating the BDNF/TrkB/CREB Signaling Pathway

Toxics
Bisphenol S (BPS) is a widespread environmental endocrine disrupter that can cause hepatotoxicity, neurotoxicity and negative effects on reproduction. Puerarin (PUE) has been found to have anti-inflammatory, antioxidant, and neuroprotective properties ...
Meilin Qin, Xinxin Guo, Nuo Xu, Yan Su, Mengfen Pan, Zhengbao Zhang, Huaicai Zeng   +6 more
doaj   +1 more source

Multifunctional Nanoscale Pigments: Emerging Risks and Circular Strategies for a Sustainable Future

Small Science, Volume 5, Issue 12, December 2025.
The growing use of nanoscale pigments drives innovation across sectors, yet raises environmental and health concerns. This article explores their multifunctional roles, emerging risks, and regulatory gaps through a One Health lens. It highlights sustainable strategies—including benign‐by‐design approaches and circular economy principles—crucial for ...
Ajay Vikram Singh, Preeti Bhardwaj, Vimal Kishore, Sunil Choudhary, Akihiko Hirose, Neha Gupta, Madleen Busse, Swarn Lata Singh, Christopher J. Osgood   +8 more
wiley   +1 more source

Patterns of Organ‐Specific Proteomic Aging in Relation to Lifestyle, Diseases, and Mortality

Aging Cell, Volume 24, Issue 12, December 2025.
We estimated 11 organ‐specific proteomic aging using the elastic net regularization model. Our findings revealed that organ‐specific proteomic aging is influenced by lifestyle factors and baseline health conditions, and can further predict all‐cause mortality and the onset of various diseases.
Qi Wang, Jingting Huang, Qida He, Mengtong Sun, Michael P. Snyder, Linyan Li   +5 more
wiley   +1 more source

Chemical safety and the exposome

Emerging Contaminants, 2023
Air pollution and rapid chemical intensification are major threats to the environment and human health. Today, we have produced over 350,000 chemicals, and current testing strategies do not meet the demands. Therefore, it is important to develop new approach methodologies (NAMs) that can help fill current information gaps.
openaire   +4 more sources

Assessing health risks from multiple environmental stressors: Moving from G×E to I×E. [PDF]

, 2018
Research on disease causation often attempts to isolate the effects of individual factors, including individual genes or environmental factors. This reductionist approach has generated many discoveries, but misses important interactive and cumulative ...
McHale, Cliona M, Morello-Frosch, Rachel, Osborne, Gwendolyn, Salmon, Andrew G, Sandy, Martha S, Smith, Martyn T, Solomon, Gina, Zeise, Lauren, Zhang, Luoping   +8 more
core   +1 more source

Exposome Boot Camp PubChemLite Lab: Cheminformatics for the Exposome

, 2021
This is the full set of materials used for the PubChemLite Lab at the Columbia Exposome Boot Camp https://www.mailman.columbia.edu/research/precision-prevention/exposome-boot-camp-measuring-exposures-omic-scale Slides and explanations: ExposomeBootCamp_PubChemLiteLab_July2021.pdf Examples: see word/PDF document: PubChemLite_MetFrag_Examples_2021.docx /
openaire   +2 more sources