Results 91 to 100 of about 1,965 (197)
Reconceptualizing and Defining Exposomics within Environmental Health: Expanding the Scope of Health Research [PDF]
Background: Exposomics, the study of the exposome, is flourishing, but the field is not well defined. The term “exposome” refers to all environmental influences and associated biological responses throughout the lifespan. However, this definition is very
Jongsma, Karin R. +2 more
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Microbial metabolites in tumor epigenetic regulation
iMeta, Volume 5, Issue 1, February 2026.The gut microbiome modulates tumor epigenetic regulation through bioactive metabolites derived from dietary substrates. Microbiota‐produced SCFAs, secondary BAs, one‐carbon metabolites, and tryptophan‐derived ligands regulate histone acetylation, DNA methylation, and chromatin remodeling via HDAC, DNMT, AhR, and metabolic cofactor‐dependent pathways ...
Wangzheqi Zhang +31 more
wiley +1 more source
Pooling samples for “top-down” molecular exposomics research: the methodology [PDF]
, 2014 BACKGROUND: Exposomics is the cutting-edge concept of screening the environmental risk factors for disease. In the novel "top-down" approach, we estimate the molecular exposome by measuring all body fluid analytes in a case-controlled study ...
Jianwen She +15 more
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Air Pollution as a Driver of Recurrent Upper-Airway Infections and Comorbid Health Issues
SinusitisAir pollution represents a critical yet modifiable factor influencing the recurrence and progression of upper-airway infections. This review explores the molecular, immunological, and environmental mechanisms linking airborne pollutants to recurrent ...
Hassan Ali +2 more
doaj +1 more source
Examining Atopic Dermatitis Through the One Health Concept Lens
Allergy, Volume 81, Issue 2, Page 345-357, February 2026.ABSTRACT This paper explores the application of the One Health framework to atopic dermatitis (AD), a complex, chronic skin disease, emphasizing interdisciplinary approaches to prevention and management. One Health integrates human, animal, environmental, and plant health, addressing challenges such as antimicrobial resistance, infectious diseases, and
Dijana Minić‐Pantić +10 more
wiley +1 more source
ToxicsBisphenol S (BPS) is a widespread environmental endocrine disrupter that can cause hepatotoxicity, neurotoxicity and negative effects on reproduction. Puerarin (PUE) has been found to have anti-inflammatory, antioxidant, and neuroprotective properties ...
Meilin Qin +6 more
doaj +1 more source
Empowering Epidemiology with Life-Based Ethics: A Study of the Exposome and Exposomics [PDF]
This dissertation examines the overarching beliefs and values driving exposomics, an innovative research venture in environmental science. Inspired by the success that the Human Genome Project had in creating technology to sequence the entire human ...
Safarlou, Caspar Willem
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State-of-the-Art Environmental Chemicals Exposomics and Metabolomics [PDF]
This Special Issue contains 13 articles—12 research papers and 1 review article. The 12 research papers focus on developing new methods for detecting specific chemical exposomes, exploring new aspects of exposome-related toxicity, applying metabolomics ...
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International Journal of Biomedical Science, 2023 Efforts to find human genes for Alzheimer Disease and for longevity have generally neglected environmental influences. Brain aging and ADRDA may be understood in the AD Exposome framework, which includes external and endogenous interactions from embryo to old age (Finch and Kulminski 2019; Finch and Haghani 2021).
openaire +1 more source
The exposome in practice: Design of the EXPOsOMICS project. [PDF]
, 2016 EXPOsOMICS is a European Union funded project that aims to develop a novel approach to the assessment of exposure to high priority environmental pollutants, by characterizing the external and the internal components of the exposome. It focuses on air and
R Vermeulen (7710689) +14 more
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