Results 81 to 90 of about 1,965 (197)

At the Right Time: Temporal Precision in Personalised Medicine

Sociology of Health &Illness, Volume 48, Issue 4, May 2026.
ABSTRACT Personalised medicine was initially heralded as delivering ‘the right drug to the right patient at the right time’. Although molecular precision has dominated recent developments, the temporal dimension has remained underexplored. This paper examines how temporal precision is emerging as a defining feature of next‐generation precision medicine,
Dominik Hofmann, Elena Esposito
wiley   +1 more source

Semantic Modeling for Exposomics with Exploratory Evaluation in Clinical Context [PDF]

, 2017
Exposome is a critical dimension in the precision medicine paradigm. Effective representation of exposomics knowledge is instrumental to melding nongenetic factors into data analytics for clinical research.
Lussier, Yves A., Jianrong Li, Jung-wei Fan, Yves A. Lussier, Fan, Jung-wei, Li, Jianrong   +5 more
core   +1 more source

Enteric Nervous System Damage by Food Contaminants: A Pathway to Neurodegeneration?

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT The enteric nervous system (ENS), a key component of the gut–brain axis, has emerged as a critical player in the pathogenesis of Parkinson's disease (PD). It is the first neural system exposed to food contaminants (FCs)—a diverse group of ubiquitous toxic compounds fortuitously present in food derived from production, processing, storage, or ...
Helena Ramos, Ana Margarida Araújo, Isabel M. P. L. V. O. Ferreira, Miguel A. Faria   +3 more
wiley   +1 more source

Chemical- and effect-oriented exposomics: Three Gorges Reservoir (TGR) [PDF]

, 2013
Exposomic studies of the rapidly changing environment of the Three Gorges Reservoir (TGR) after its impounding is elaborated as a novel field of human and environmental research.
Wang, Jingxian, Schramm, Karl-Werner, Temoka, Cedrique, Scherb, Hagen, Schramm, KW (reprint author), German Res Ctr Environm Hlth GmbH, Helmholtz Zentrum Munchen, Mol EXpos MEX, Ingolstadter Landstr 1, D-85764 Neuherberg, Germany., Pfister, Gerd, Henkelmann, Bernhard, Bi, Yonghong   +7 more
core   +1 more source

Decoding the “Metallic” Immune Imprint: Single‐Cell Exposomics Reveals the Immune Imprint of Fire Smoke

Allergy, EarlyView.
Takafumi Kubota, Yuki Matsumoto, Takahiro Tabuchi   +2 more
wiley   +1 more source

Mixture of organic pollutants is associated with cognitive aging

Alzheimer's &Dementia, Volume 22, Issue 4, April 2026.
Abstract INTRODUCTION Environmental organic pollutants impact brain function and cognitive aging, but the effect of real‐world complex mixtures of these pollutants is unexplored. METHODS Using data collected at two time points from 170 cognitively normal adults, we used hierarchical Bayesian kernel machine regression to examine the association between ...
Vrinda Kalia, Katherine E. Manz, Jaime Benavides, Suhang Song, Brandi L. Vollmer, Beizhan Yan, Jeff Goldsmith, Kurt D. Pennell, Yaakov Stern, Marianthi‐Anna Kioumourtzoglou, Gary W. Miller, Christian Habeck, Yian Gu   +12 more
wiley   +1 more source

Customized webgis solutions for exposomics [PDF]

, 2020
Exposomics is a science aiming at quantifying the effects on human health of all the factors influencing it, but genetic ones. They include environment, food, mobility habits and cultural factors.
Fiscante N., Rocca M. T., Sapio F., Casella V., Raso L., Pogliaghi A., Franzini M.   +6 more
core   +1 more source

Scientific knowledge about dementia: From the Global South to the world

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract Most people with dementia live in low‐ and middle‐income countries (LMICs), but scientific knowledge about dementia is dominated by Global North perspectives. This interdisciplinary article combines expertise from Latin America, India, and Europe, using a mixed‐methodology approach that incorporates expert discussions, a narrative review, and ...
Timothy Daly, Ignacio López‐Barrenechea, Paulina Vergara, Faheem Arshad, Avanthi Paplikar, Aparajita Ray Chaudhuri, Lucía Crivelli, Agustín Ibáñez, Suvarna Alladi, Andrea Slachevsky   +9 more
wiley   +1 more source

Human Systems Immunology in the Omics Era: Challenges, Methods, and Emerging Directions

European Journal of Immunology, Volume 56, Issue 3, March 2026.
Systems immunology provides a transformative framework for decoding human immune complexity. This review evaluates high‐throughput technologies and provides a roadmap for navigating analytical challenges—such as batch effects and interindividual heterogeneity—to successfully translate multimodal data into meaningful biological insights.
Lennart Riemann, Reinhold Förster
wiley   +1 more source

From the Gut to the Brain: Microplastic‐Associated Neurovascular Dysfunction and Implications for Stroke Risk

Advanced Science, Volume 13, Issue 11, 23 February 2026.
Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang, Yujiao He, Pei Zou, Xiaoyi Wang, Gang Peng, Xiangying Deng   +5 more
wiley   +1 more source