Results 281 to 290 of about 528,613 (372)

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Exploring the host parasitism of the migratory plant-parasitic nematode Ditylenchus destuctor by expressed sequence tags analysis. [PDF]

PLoS One, 2013
Peng H, Gao BL, Kong LA, Yu Q, Huang WK, He XF, Long HB, Peng DL.   +7 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Tandem solubility enhancing tags enable the heterologous expression and <i>in vitro</i> maturation of a class IIa bacteriocin, clesteriocin a, identified in <i>Candidatus Clostridium mucoides</i> CM038. [PDF]

Front Microbiol
Wambui J, Tasara T, Bigler L, Stephan R.
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Absolute quantification of fluorescent protein fusions by mass spectrometry. [PDF]

Protein Sci
Shevchenko A, Ghosh A, Schuhmann A, Bogdanova A, Thomas H, Rao V, Geertsma ER, Dora Tang TY, Shevchenko A.   +8 more
europepmc   +1 more source

Computational identification of miRNA and targets from expressed sequence tags of coffee (Coffea arabica). [PDF]

Saudi J Biol Sci, 2014
Akter A, Islam MM, Mondal SI, Mahmud Z, Jewel NA, Ferdous S, Amin MR, Rahman MM.   +7 more
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Gene expression profiling of human HBV- and/or HCV-associated hepatocellular carcinoma cells using expressed sequence tags

, 2006
Sun Young Yoon, Jeong‐Min Kim, Jung‐Hwa Oh, Yeo-Jin Jeon, Dong‐Seok Lee, Joo H. Kim, Jong Hyun Choi, Byung Zun Ahn, Sang Soo Kim, Hyang‐Sook Yoo, Yong Kim, Nam-Soon Kim   +11 more
openalex   +2 more sources

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source