Results 111 to 120 of about 33,209,906 (421)
Partition Decoupling for Multi-gene Analysis of Gene Expression Profiling Data [PDF]
, 2011 We present the extention and application of a new unsupervised statistical learning technique--the Partition Decoupling Method--to gene expression data.
Braun, Rosemary +3 more
core +5 more sources
Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
FEBS Letters, EarlyView.Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga +6 more
wiley +1 more source
Frontiers in Plant Science, 2017 Fructose-1, 6-bisphosphate aldolase (FBA) is a key plant enzyme that is involved in glycolysis, gluconeogenesis, and the Calvin cycle. It plays significant roles in biotic and abiotic stress responses, as well as in regulating growth and development ...
Geng-Yin Lv +13 more
doaj +1 more source
The intrinsic stiffness of human trabecular meshwork cells increases with senescence. [PDF]
, 2015 Dysfunction of the human trabecular meshwork (HTM) plays a central role in the age-associated disease glaucoma, a leading cause of irreversible blindness.
Chang, Yow-Ren +4 more
core +3 more sources
Nonparametric expression analysis using inferential replicate counts
bioRxiv, 2019 A primary challenge in the analysis of RNA-seq data is to identify differentially expressed genes or transcripts while controlling for technical biases. Ideally, a statistical testing procedure should incorporate the inherent uncertainty of the abundance
Anqi Zhu +4 more
semanticscholar +1 more source
FEBS Letters, EarlyView.The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva +1 more
wiley +1 more source
Genetics and Molecular Biology, 2014 Two somatic embryogenesis receptor-like kinase genes (identified as AcSERK1 and AcSERK2) have previously been characterized from pineapple (Ananas comosus). In this work, we describe the characterization of a third gene (AcSERK3) in this family.
Jun Ma +9 more
doaj +1 more source
Analysis of microRNAs expressions in chondrosarcoma [PDF]
Journal of Orthopaedic Research, 2013 AbstractMicroRNAs (miRNAs) are small non‐coding RNAs capable of inhibiting gene expression post‐transcriptionally and expression profiling can provide therapeutic targets and tools for cancer diagnosis. Chondrosarcoma is a mesenchymal tumor with unknown cause and differentiation status.
Kazutaka Kikuta +8 more
openaire +3 more sources
A higher Angiogenin expression is associated with a non-nuclear Maspin location in laryngeal carcinoma [PDF]
, 2015 Objectives. In numerous malignancies, angiogenin (ANG) and Maspin are important proangiogenic and antiangiogenic regulators, respectively. The aim of this study was to identify potential relationships between the biological roles of these two proteins in
Blandamura, Stella +7 more
core +2 more sources
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source