Results 111 to 120 of about 31,723,480 (301)

Cross-Platform Analysis with Binarized Gene Expression Data

, 2009
With widespread use of microarray technology as a potential diagnostics tool, the comparison of results obtained from the use of different platforms is of interest.
Tuna, Salih, Niranjan, Mahesan
core   +2 more sources

Evaluating the molecular function of zebrafish Anoctamin 1a

microPublication Biology
Calcium-activated chloride channels (CaCCs) regulate key physiological processes like epithelial secretion, sensory transduction, gastrointestinal pacemaking, and muscle contraction.
Amanda Dimatteo, Nicole Stango, Adam Rich, Tara Sweet   +3 more
doaj   +1 more source

Data Mining for Expressivity of Recombinant Protein Expression

Transactions of the Japanese Society for Artificial Intelligence, 2006
We analyzed the expressivity of recombinant proteins by using data mining methods. The expression technique of recombinant protein is a key step towards elucidating the functions of genes discovered through genomic sequence projects. We have studied the productive efficiency of recombinant proteins in fission yeast, Schizosaccharomyces pombe (S.pombe),
KIRA, Satoshi, ISOAI, Atsushi, YAMAMURA, Masayuki   +2 more
openaire   +2 more sources

Bayesian hierarchical clustering for studying cancer gene expression data with unknown statistics [PDF]

, 2013
Clustering analysis is an important tool in studying gene expression data. The Bayesian hierarchical clustering (BHC) algorithm can automatically infer the number of clusters and uses Bayesian model selection to improve clustering quality. In this paper,
Muhammad F Bari, Bari Muhammad F., Sirinukunwattana Korsuk, Bari, Muhammad F., Muhammad F. Bari, Savage, Richard S., David R. J. Snead, David R. J. Snead (475600), Richard S Savage, Richard S. Savage, Rajpoot Nasir M., Muhammad F. Bari (417733), Snead, David R. J., David R J Snead, Richard S. Savage (341629), Nasir M. Rajpoot, Korsuk Sirinukunwattana (475599), Rajpoot, Nasir M., Sirinukunwattana, Korsuk, Korsuk Sirinukunwattana, Snead, David R.J., Snead David R. J., Nasir M. Rajpoot (185555), Nasir M Rajpoot, Savage Richard S.   +24 more
core   +2 more sources

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Depletion of UNK-1 affects head locomotive behaviors in Caenorhabditis elegans

microPublication Biology
During development, transcription factors execute genetic programs to define and shape the nervous system. We previously reported the transcription factor EGL-43/Mecom regulates expression of numerous genes important for neuronal development in C ...
Lexin Gitler, Callista Yee
doaj   +1 more source

Integration of expression data in genome-scale metabolic network reconstructions

Frontiers in Physiology, 2012
With the advent of high-throughput technologies, the field of systems biology has amassed an abundance of omics data, quantifying thousands of cellular components across a variety of scales, ranging from mRNA transcript levels to metabolite quantities ...
Anna S. Blazier, Jason A. Papin
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

The CFII components PCF11 and Cbc change subnuclear localization as cells differentiate in an adult stem cell lineage

microPublication Biology
Stage specific increased expression of PCF11 and Cbc, the two components of Cleavage Factor complex II, contribute to developmentally regulated 3’UTR shortening due to alternate polyadenylation of nascent RNA molecules in Drosophila spermatocytes.
Iliana Nava, Margaret T. Fuller, Lorenzo Gallicchio   +2 more
doaj   +1 more source

J-Express: exploring gene expression data using Java

Bioinformatics, 2001
Abstract Summary: J-Express is a Java application that allows the user to analyze gene expression (microarray) data in a flexible way giving access to multidimensional scaling, clustering, and visualization methods in an integrated manner.
B. Dysvik, Inge Jonassen
openaire   +3 more sources