Results 91 to 100 of about 3,834 (197)

The Tap‐to‐Safety Task: A Novel fMRI Paradigm Assessing Repetitive Threat‐Neutralization

Human Brain Mapping, Volume 47, Issue 3, 15 February 2026.
In this study, we present a novel task to model repetitive threat‐neutralization behavior during neuroimaging. Results suggest that the dorsal anterior cingulate cortex (dACC), anterior insula, and dorsal striatum interact to drive neutralization behavior in the face of perceived threats.
Hannah Berg, Riley Rozniarek, Aardron Robinson, Rayus Kuplicki, Annette Rostel, Nate Mungunkhet, Ryan Smith, H. Blair Simpson, Martin P. Paulus, Robin L. Aupperle   +9 more
wiley   +1 more source

Osteopoikilosis and multiple exostoses caused by novel mutations in LEMD3 and EXT1 genes respectively - coincidence within one family

BMC Medical Genetics, 2010
Background Osteopoikilosis is a rare autosomal dominant genetic disorder, characterised by the occurrence of the hyperostotic spots preferentially localized in the epiphyses and metaphyses of the long bones, and in the carpal and tarsal bones 1 ...
Horn Denise, Kolanczyk Mateusz, Jamsheer Aleksander, Baasanjav Sevjidmaa, Latos Tomasz, Hoffmann Katrin, Latos-Bielenska Anna, Mundlos Stefan   +7 more
doaj   +1 more source

The Metacarpophalangeal Pattern Profile: An Old Method With New Insights Into the Evaluation of Short Stature

American Journal of Human Biology, Volume 38, Issue 2, February 2026.
ABSTRACT Objective To characterize the metacarpophalangeal pattern profile (MCPP) of healthy children and adolescents from São Paulo, Brazil, and to establish percentile curves by chronological age (CA), bone age (BA), and sex using the LMS method. Additionally, to compare these findings with previous population‐based data and to apply the derived ...
Marcelo Damaso Maruichi, Bruno Telma Destailleur, Giulia Maesta Apelbaum, Carlos Alberto Longui, Cristiane Kochi   +4 more
wiley   +1 more source

Novel EXT1 mutation identified in a pedigree with hereditary multiple exostoses

Oncology Reports, 2013
Hereditary multiple exostoses (HME) is an autosomal dominant bone disorder characterized by the presence of multiple benign cartilage-capped tumors. EXT1 located on chromosome 8q23-q24 and EXT2 located on 11p11-p12 are the main disease-causing genes which are responsible for ~90% of HME cases.
Li, Cao, Fei, Liu, Mingxiang, Kong, Yong, Fang, Haifeng, Gu, Yu, Chen, Chen, Zhao, Shuijun, Zhang, Qing, Bi   +8 more
openaire   +3 more sources

Summary of the cardiac phenotype in Ext1 mutants.

, 2015
Summary of the cardiac phenotype in Ext1 mutants.
Yan Chen (4308), Zhongzhou Yang (223241), Zhenzhen Wang (250368), Jiu-Lin Wu (785723), Yi Pan (68170), Peijuan Cao (785722), Rui Zhang (13940)   +6 more
core   +1 more source

Integrative cross‐tissue and spatially resolved single‐cell profiling uncovers tumour‐educated inflammatory remodelling of tissue‐resident macrophage ecosystem with immunotherapeutic prognostic significance in pan‐cancer

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
Pan‐cancer analysis reveals an inflammatory phenotype remodeling of tissue‐resident macrophages (iTRM) in the tumor microenvironment, which is associated with immunosuppression. Tissue‐resident macrophages and monocyte‐derived macrophages exhibit convergent differentiation toward a similar inflammatory phenotype. iTRM‐enriched ecosystems are associated
Weikai Wang, Zibin Chen, Yuhan Huang, Zhihao Hu, Peixin Zhu, Zhuoli Huang, Jingzhi Lv, Ziru Liao, Yuhui Zheng, Chen Wei, Baibing Guan, Yin Zeng, Xinyue Zhu, Yafei Yang, Guibo Li, Xin Jin, Xi Chen, Xiao Yang, Zikun Ma, Jianhua Yin   +19 more
wiley   +1 more source

Hereditary Multiple Exostoses: Current Insights

Orthopedic Research and Reviews, 2019
Antonio D’Arienzo, Lorenzo Andreani, Federico Sacchetti, Simone Colangeli, Rodolfo Capanna Department of Translational Research on New Surgical and Medical Technologies, University of Pisa, Pisa, ItalyCorrespondence: Federico SacchettiDepartment of
D'Arienzo A, Andreani L, Sacchetti F, Colangeli S, Capanna R   +4 more
doaj  

Epithelial heparan sulfate regulates Sonic Hedgehog signaling in lung development.

PLoS Genetics, 2017
The tree-like structure of the mammalian lung is generated from branching morphogenesis, a reiterative process that is precisely regulated by numerous factors.
Hua He, Meina Huang, Shenfei Sun, Yihui Wu, Xinhua Lin   +4 more
doaj   +1 more source

The elusive functions of EXT1 and EXT2

, 2021
M.Phil.
openaire   +1 more source

Identifying early changes in imaging, plasma, and digital cognitive biomarkers that correspond to Alzheimer's disease pathology in the presence of autopsy‐confirmed co‐pathologies

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION Alzheimer's disease (AD) biomarkers are assessed on their ability to detect AD pathophysiology in vivo, with confirmation of AD neuropathology only at autopsy. METHODS Positron emission tomography (PET), plasma, and cognitive AD biomarkers were compared to AD neuropathology in Harvard Aging Brain Study participants (10 cognitively
Charles D. Chen, Cinthya Aguero, Alexandra Melloni, Brian C. Healy, Emma G. Thibault, Jessie Fanglu Fu, Michelle E. Farrell, Stephanie Schultz, Hyun‐Sik Yang, Jean‐Pierre Bellier, Jasmeer Chhatwal, Pia Kivisäkk Webb, Steven Arnold, Dana Penney, Randall Davis, Dorene Rentz, Teresa Gomez‐Isla, Reisa A. Sperling, Keith A. Johnson, Julie C. Price   +19 more
wiley   +1 more source