Results 81 to 90 of about 4,149 (184)
Structural basis for heparan sulfate co-polymerase action by the EXT1–2 complex [PDF]
, 2023 Hua Li +5 more
openalex +1 more source
Advanced Science, Volume 12, Issue 32, August 28, 2025.Schwann cells may facilitate intracranial plaque progression via neurovascular remodelingcting with vascular smooth muscle cells in atherosclerotic plaques, with the SPP1 ‐ ITGB1 signaling axis mediating this interaction as a novel mechanism. Abstract Intracranial atherosclerosis (ICAS), a common cause of ischemic stroke, remains a therapeutic ...
Zijue Wang +10 more
wiley +1 more source
Clinical Case Reports, Volume 13, Issue 8, August 2025.ABSTRACT A 17‐year‐old male patient with a c.2065C>T heterozygous nonsense mutation in the TRPS1 gene has sparse, soft hair; short thumbs and toes; misaligned teeth; and X‐ray findings of short distal thumb phalanges, depressed middle finger phalanges bases, and short toe proximal phalanges.
Cailing E. +5 more
wiley +1 more source
Anticancer Molecular Mechanisms of Epigallocatechin Gallate: An Updated Review on Clinical Trials
Food Science &Nutrition, Volume 13, Issue 8, August 2025.Epigallocatechin gallate (EGCG), a bioactive compound abundantly exists in green tea and grapes with strong antioxidant activity and anticancer potential is a suitable approach to reduce the cancer burden. The invitro and invivo anticancer studies of EGCG proved anticancer and anti‐tumor effect through modulation of cancer signaling pathways, reduction
Ahmad Mujtaba Noman +13 more
wiley +1 more source
Changes in multi‐gene cancer panels for children: A 4‐year retrospective review
Journal of Genetic Counseling, Volume 34, Issue 4, August 2025.Abstract The multi‐gene panel is the most utilized genetic test to evaluate for germline cancer predisposition syndromes. However, the rate of change of commercial multigene panels is not well understood, and its value as a standalone test has also not been investigated.
Elise G. Williams +4 more
wiley +1 more source
Hereditary Multiple Exostoses: Clinical, Molecular and Radiologic Survey in 9 Families
Prague Medical Report, 2017 Hereditary multiple exostoses (HME) represents a heterogeneous group of diseases often associated with progressive skeletal deformities. Most frequently, mutations in EXT1 and EXT2 genes with autosomal dominant inheritance are responsible for HME. In our
Karel Medek +9 more
doaj +1 more source
Heparan Sulfate Synthesized by Ext1 Regulates Receptor Tyrosine Kinase Signaling and Promotes Resistance to EGFR Inhibitors in GBM [PDF]
, 2020 Yuki Ohkawa +9 more
openalex +1 more source
Hereditary Cancer in Clinical Practice, 2004 Multiple Osteochondromas is an autosomal dominant disorder characterised by the presence of multiple osteochondromas and a variety of orthopaedic deformities.
Hameetman Liesbeth +4 more
doaj +1 more source