Results 31 to 40 of about 492,732 (252)

Study of Spectroscopic, Thermal, Microscopic Characteristics and Extended-Release Application of Carboxymethyl Ethyl Cellulose

Polysaccharides
Carboxymethyl ethyl cellulose (CMEC), a pH-sensitive polymer listed in Japanese Pharmaceutical Excipients (JPE), 2013, has seldom been characterized and explored for drug delivery.
Ankita Thorat, Amarjitsing Rajput, Prashant Pisal, Rahul Aware, Sandeep Kulkarni, Darshan Telange, Madhur Kulkarni   +6 more
doaj   +1 more source

Combatting pain after orthopedic/trauma surgery- perioperative oral extended-release tapentadol vs. extended-release oxycodone/naloxone

BMC Anesthesiology, 2017
Background High post-operative pain scores after “minor” orthopedic/trauma surgery are in part attributed to inadequate prescription of opioid analgesics.
Gertrud Haeseler, Dirk Schaefers, Natalie Prison, Jörg Ahrens, Xiaofei Liu, Annika Karch   +5 more
doaj   +1 more source

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Features of the extended-release metformin

Ожирение и метаболизм, 2013
Реферат по материалам статьи Ali S, Fonseca V. Overview of metformin: special focus on metformin extended release. Expert Opin Pharmacother. 2012 Aug;13(12):1797-805.

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Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Analgesic efficacy, safety, and tolerability of a long-acting abuse-deterrent formulation of oxycodone for moderate-to-severe chronic low back pain in subjects successfully switched from immediate-release oxycodone

Journal of Pain Research, 2018
John Markman,1 Diana S Meske,2 Ernest A Kopecky,2 Ben Vaughn,3 Melinda L O’Connor,2 Steven D Passik2 1Department of Neurosurgery, Translational Pain Research Program, University of Rochester, Rochester, NY, USA; 2Collegium Pharmaceutical Inc.,
Markman J, Meske DS, Kopecky EA, Vaughn B, O'Connor ML, Passik SD   +5 more
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A study on design & development of betamethasone acetate and betamethasone sodium phosphate extended-release suspension

Journal of Applied Pharmaceutical Research
Background: The development of an injectable composition of betamethasone sodium phosphate and betamethasone acetate with an equivalent drug release profile to the marketed reference drug product, "Celestone Soluspan®," is highly challenging. To overcome
Amit Bansal, Satish Sardana, Tarun Wadhwa   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Comparison of immediate release and extended release formulations in therapy

Psychiatry and Clinical Psychopharmacology, 2021
The pharmacokinetics of drugs determine some of the parameters such as the dosing frequency, the route of administration, starting dose , time to reach the steadystate concentration etc.
Yağız Üresin, Elif Baran
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