Results 21 to 30 of about 5,492,450 (303)

Nitroheterocyclic drug resistance mechanisms in Trypanosoma brucei [PDF]

open access: yes, 2016
Objectives The objective of this study was to identify the mechanisms of resistance to nifurtimox and fexinidazole in African trypanosomes. Methods Bloodstream-form Trypanosoma brucei were selected for resistance to nifurtimox and fexinidazole by ...
Kelner, Anna   +5 more
core   +1 more source

A CLINICAL CASE OF EFFECTIVE TREATMENT OF EXTENSIVE DRUG RESISTANCE TUBERCULOSIS WITH NEW ANTI-TUBERCULOSIS DRUGS

open access: yesТуберкулез и болезни лёгких, 2018
The article presents a clinical case of effective treatment of a female patient suffering from respiratory tuberculosis with extensive drug resistance. Chemotherapy regimen included 7 drugs, including bedaquiline and perchlozon.
M. V. Pаvlovа   +5 more
doaj   +1 more source

Extensively drug-resistant Salmonella typhi causing rib osteomyelitis: A case report

open access: yesAsian Pacific Journal of Tropical Medicine, 2021
Rationale: Salmonella (S.) typhi is a rare cause of osteomyelitis in immunocompetent adults. Extensive drug resistance (XDR) may lead to more complicated cases of S. typhi osteomyelitis.
Sara Iqbal, Humza Thobani, Saulat Fatimi
doaj   +1 more source

Multidrug-Resistant Tuberculosis and Extensively Drug-Resistant Tuberculosis [PDF]

open access: yesCold Spring Harbor Perspectives in Medicine, 2015
The continuing spread of drug-resistant tuberculosis (TB) is one of the most urgent and difficult challenges facing global TB control. Patients who are infected with strains resistant to isoniazid and rifampicin, called multidrug-resistant (MDR) TB, are practically incurable by standard first-line treatment.
Kwonjune J, Seung   +2 more
openaire   +2 more sources

ANALYSIS OF THE PATIENTS REFERRED FOR TREATMENT TO NOVOSIBIRSK TUBERCULOSIS RESEARCH INSTITUTE FROM THE AREAS SUPERVISED BY THIS INSTITUTE. CHANGES IN CHEMOTHERAPY EFFICIENCY AFTER INTRODUCTION OF THE UPDATED TREATMENT REGIMENS AND MICROBIOLOGICAL DIAGNOSTICS

open access: yesТуберкулез и болезни лёгких, 2017
In 2015 the implementation of Edicts no. 951 by the Russian Ministry of Health On Guidelines on Improvement of Respiratory Tuberculosis Treatment and Diagnostics was started.Goal of the study: to analyze the characteristics of tuberculosis patients ...
E. P. Myshkova   +2 more
doaj   +1 more source

"Plasmodium falciparum" Drug Resistance, Molecular Genotyping and Generation of a Malaria Resistance Genogram by DNA Microarray-Based Technology [PDF]

open access: yes, 2006
Prior to the 2001 malarial treatment policy change in Tanzania, studies were conducted to assess the efficacy of sulfadoxine-pyrimethamine (SP) and usefulness of molecular markers in monitoring SP resistance.
Mugittu, Kefas Nasongelya
core   +1 more source

Trends in Drug Resistance of Acinetobacter baumannii over a 10-year Period: Nationwide Data from the China Surveillance of Antimicrobial Resistance Program

open access: yesChinese Medical Journal, 2017
Background: Acinetobacter baumannii has emerged as an important pathogen causing a variety of infections. Using data from the China Surveillance of Antimicrobial Resistance Program conducted biennially, we investigated the secular changes in the ...
Lei Gao, Yuan Lyu, Yun Li
doaj   +1 more source

Spread of Extensively Drug-resistant Tuberculosis

open access: yesEmerging Infectious Diseases, 2007
To the Editor: An emergency has been declared in KwaZulu Natal, South Africa, where an outbreak of 53 cases of a highly lethal form of tuberculosis (TB) has occurred (1,2). This outbreak was caused by an extensively drug-resistant TB (XDR TB) strain.
Sofía Samper, Carlos Martín
openaire   +3 more sources

Explaining risk factors for drug-resistant tuberculosis in England and Wales: contribution of primary and secondary drug resistance [PDF]

open access: yes, 2004
Drug-resistant tuberculosis can be transmitted (primary) or develop during the course of treatment (secondary). We investigated risk factors for each type of resistance.
Glynn, JR   +5 more
core   +1 more source

MDR and XDR typhoid fever-a threat for the current decade?

open access: yesThe Pan African Medical Journal, 2021
Salmonella typhi is a gram-negative, flagellated, rod-shaped bacterium that is responsible for typhoid fever. Salmonella typhi infections are found only in humans and are spread by polluted water sources and poor hygiene practices, such as fecal ...
Manas Pustake   +2 more
doaj   +1 more source

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