The 5th CIHLMU Infectious Disease Symposium, Munich, Germany, March 12, 2016 brought together Tuberculosis Experts from developed and low middle-income countries to discuss the control of drug resistance Tuberculosis. The meeting featured 9 presentations:
Celso Khosa +5 more
doaj +1 more source
Sequence analyses of just four genes to detect extensively drug-resistant Mycobacterium tuberculosis strains in multidrug-resistant tuberculosis patients undergoing treatment [PDF]
The rapid detection of Mycobacterium tuberculosis isolates resistant to second-line drugs is crucial for the institution of appropriate treatment regimens as early as possible.
Feuerriegel, S +6 more
core +2 more sources
Summary: This study describes the first case of extensively drug-resistant tuberculosis (XDR-TB) in the Thames Valley and South East Region and discuss the public health implications, highlighting the need to integrate current epidemiological knowledge ...
Muhammad Abid +6 more
doaj +1 more source
Fluoroquinolone Efficacy against Tuberculosis Is Driven by Penetration into Lesions and Activity against Resident Bacterial Populations. [PDF]
Fluoroquinolones represent the pillar of multidrug-resistant tuberculosis (MDR-TB) treatment, with moxifloxacin, levofloxacin, or gatifloxacin being prescribed to MDR-TB patients.
Alvarez-Cabrera, Nadine +16 more
core +2 more sources
Treatment outcomes for children with multidrug-resistant tuberculosis: a systematic review and meta-analysis [PDF]
BACKGROUND: Paediatric multidrug-resistant (MDR) tuberculosis is a public health challenge of growing concern, accounting for an estimated 15% of all global cases of MDR tuberculosis. Clinical management is especially challenging, and recommendations are
Abubakar +42 more
core +2 more sources
To reconstruct transmission chains of the multidrug-resistant tuberculosis Ch strain, which harbors a unique combination of resistance mutations, we analyzed genomes of 25 isolates from 12 patients with diagnosis during 2006–2022 in Chaco Province ...
Roxana Paul +13 more
doaj +1 more source
Resistance patterns and trends of extensively drug-resistant tuberculosis: 5-year experience [PDF]
Objective:Extensively drug-resistant tuberculosis (XDR-TB) strains were emerged when multidrug-resistant TB (MDR- TB) was inadequately treated. Inadequate treatment of MDR-TB cases may result in additional resistance especially non-XDR-TB and then XDR ...
Amresh Kumar Singh +6 more
doaj +1 more source
Challenges and Controversies in Defining Totally Drug-Resistant Tuberculosis
In March 2012, in response to reports of tuberculosis (TB) resistant to all anti-TB drugs, the World Health Organization convened an expert consultation that identified issues to be resolved before defining a new category of highly drug-resistant TB ...
Peter Cegielski +8 more
doaj +1 more source
Resistance to Second-Line Anti-TB Drugs in Cambodia: A Phenotypic and Genetic Study
Sokleaph Cheng,1– 3 Mallorie Hide,3– 5 Sok Heng Pheng,6 Alexandra Kerléguer,2 Gauthier Delvallez,2 Sophan Sam,7 Tan Eang Mao,6 Thi Van Anh Nguyen,3,8 Anne-Laure Bañuls3– 5 1Institut Pasteur du Cambodge and Ministry of ...
Cheng S +8 more
doaj
Rationing tests for drug-resistant tuberculosis - who are we prepared to miss? [PDF]
BACKGROUND: Early identification of patients with drug-resistant tuberculosis (DR-TB) increases the likelihood of treatment success and interrupts transmission.
A Faustini +35 more
core +4 more sources

