Neoteric advancement in TB drugs and an overview on the anti-tubercular role of peptides through computational approaches [PDF]
Peptides of varied origins such as human immune cells and non-immune cells, bacteria, fungi, and venoms have been widely investigated as anti-tubercular agents for the replacement of existing anti-tubercular drugs in future.
Aarti, Chirom +7 more
core
Molecular detection and characterization of drug-resistant Mycobacterium tuberculosis [PDF]
Tuberculosis (TB) is an ancient disease, but not a disease of the past. Despite the declaration of TB as a global emergency by the World Health Organization in 1993 the worldwide problem of TB has worsened.
Engström, Anna
core +2 more sources
XDR TB in South Africa - What lies ahead?
The emergence of XDR TB coupled with the high prevalence of HIV/AIDS has intensified the need to identify new treatment strategies and accelerate research into antibiotics against XDR TB before the world is faced with a global public health crisis.
V. Thaver, Gboyega A. Ogunbanjo
doaj +1 more source
Can we prevent antimicrobial resistance by using antimicrobials better? [PDF]
Since their development over 60 years ago, antimicrobials have become an integral part of healthcare practice worldwide. Recently, this has been put in jeopardy by the emergence of widespread antimicrobial resistance, which is one of the major problems ...
Brown +27 more
core +2 more sources
Drug-Resistant Tuberculosis, KwaZulu-Natal, South Africa, 2001–2007
In Africa, incidence and prevalence of drug-resistant tuberculosis have been assumed to be low. However, investigation after a 2005 outbreak of extensively drug-resistant tuberculosis in KwaZulu-Natal Province, South Africa, found that the incidence rate
Kristina Wallengren +11 more
doaj +1 more source
Mental disorders and drug/alcohol use in patients commencing extensively drug-resistant tuberculosis treatment. [PDF]
Mental disorders and alcohol/drug use worsen treatment outcomes for multidrug-resistant tuberculosis (TB), but data are lacking for extensively drug-resistant (XDR) TB.
Boccia, D +6 more
core +1 more source
Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis [PDF]
New therapeutic strategies are needed to combat the tuberculosis pandemic and the spread of multidrug-resistant (MDR) and extensively drug-resistant (XDR) forms of the disease, which remain a serious public health challenge worldwide1, 2. The most urgent
A Koul +89 more
core +3 more sources
Repurposing and Revival of the Drugs: A New Approach to Combat the Drug Resistant Tuberculosis
Emergence of drug resistant tuberculosis like multi drug resistant tuberculosis (MDR-TB), extensively drug-resistant tuberculosis (XDR-TB) and totally drug resistant tuberculosis (TDR-TB) has created a new challenge to fight against these bad bugs of ...
Divakar Sharma +4 more
doaj +1 more source
Trends of Zambia’s tuberculosis burden over the past two decades [PDF]
Objectives: To study trends in Zambia’s TB notification rates between 1990 and 2010 and to ascertain progress made towards TB control. Methods: Retrospective review of TB notification returns and TB programme reports for the period from 1990 to 2010 ...
Ahmed +26 more
core +1 more source
Abstract Background: Multidrug-resistant tuberculosis (MDRTB) is a growing global health concern that is a chronic danger to world health due to tuberculosis (TB). Objective: The aim of this study was to examine the frequency of both pre extensively drug-resistant tuberculosis (PXDRTB) and extensively drug-resistant tuberculosis (EXDRTB) in patients ...
Salman khan +3 more
openaire +1 more source

