Results 71 to 80 of about 1,639,942 (291)
Adaptation of Revised Social Anhedonia Scale (RSAS) on Russian sample
Консультативная психология и психотерапия, 2016 Anhedonia (or hypohedonia) reflects a missing or reduced ability to experience pleasure. Interest in the concept of clinical psychology and psychopathology is due to the high significance of violations of ability to experience pleasure as a predictor of ...
Rychkova O.V., Kholmogorova A.B.
doaj +1 more source
Dark solitons at nonlinear interfaces [PDF]
, 2010 The refraction of dark solitons at a planar boundary separating two defocusing Kerr media is simulated and analyzed, for the first time (to our knowledge). Analysis is based on the nonlinear Helmholtz equation and is thus valid for any angle of incidence.
Aceves +31 more
core +2 more sources
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
External validity in perinatal research [PDF]
Acta Obstetricia et Gynecologica Scandinavica, 2017 AbstractRecent studies are beginning to focus on the external validity of well conducted internally valid research. This review gives an overview of external validity, the dimensions involved and suggestions for when future intervention trials are designed, using examples from perinatal research.
Anthony O. Odibo, Ganesh Acharya
openaire +2 more sources
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
A General Algorithm for Deciding Transportability of Experimental Results
Journal of Causal Inference, 2013 Generalizing empirical findings to new environments, settings, or populations is essential in most scientific explorations. This article treats a particular problem of generalizability, called “transportability”, defined as a license to transfer ...
Bareinboim Elias, Pearl Judea
doaj +1 more source
Use of a 3-item short-form version of the Barthel Index for use in stroke: systematic review and external validation [PDF]
, 2017 Background and Purpose—There may be a potential to reduce the number of items assessed in the Barthel Index (BI), and shortened versions of the BI have been described.
Ali, Myzoon +5 more
core +2 more sources
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
The Deductive Approach to Causal Inference
Journal of Causal Inference, 2014 This paper reviews concepts, principles, and tools that have led to a coherent mathematical theory that unifies the graphical, structural, and potential outcome approaches to causal inference. The theory provides solutions to a number of pending problems
Pearl Judea
doaj +1 more source
RE-AIM Planning and Evaluation Framework: Adapting to New Science and Practice With a 20-Year Review
Frontiers in Public Health, 2019 The RE-AIM planning and evaluation framework was conceptualized two decades ago. As one of the most frequently applied implementation frameworks, RE-AIM has now been cited in over 2,800 publications.
Russell E. Glasgow +11 more
doaj +1 more source