Results 81 to 90 of about 17,437,503 (278)

Extra-cranial and extra-axial tumor development.

, 2019
A. Extra-cranial and extra-axial tumor development on CE-T1w image. B. In vivo serial CE-T1w MRI scans in the same rat showing extra-axial tumor development.
Luc Leybaert (313676), Ingeborg Goethals (849158), Karel Deblaere (3079569), Leen Pieters (7522208), Christian Vanhove (772792), Valerie De Meulenaere (6065855), Olivier De Wever (6885914), Ellen Bonte (7522202), Anne Vral (3432671), Benedicte Descamps (772793), Jeroen Verhoeven (3821551), Jean-Pierre Kalala Okito (7522205)   +11 more
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Linking performance appraisal fairness and performance feedback to bankers’ extra-role customer service behavior: A serial multiple mediation model

Social Sciences and Humanities Open
The study aims to evaluate the influence of performance appraisal fairness and performance feedback on extra-role customer service behavior directly and indirectly through organizational commitment and work engagement in the banking sector of Bangladesh.
Dewan Niamul Karim, Md. Mosharref Hossain, Suman Paul Chowdhury, Rashed Al Karim, Md. H Asibur Rahman, Md. Siddikur Rahman   +5 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

THE MEDIATION ROLE OF EXTRA ROLE: ORGANIZATIONAL SUPPORT AND INFORMATION TECHNOLOGY ON EMPLOYEE PERFORMANCE

EKUITAS (Jurnal Ekonomi dan Keuangan)
The purpose of this study is to test and analyze the mediation role of extra role behavior on the influence of organizational support and information technology on Micro Small and Medium Enterprises (MSME) actors. Method in this study is a quantitative study.
Nurlasera Nurlasera, Uzoma Ononye, Qori Al Banin, Mayaastuti Mayaastuti, Yusmedi Nur Faizal   +4 more
openaire   +2 more sources

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

The role of extra time in the performance of students with learning disabilities in time-constrained assessment

Cogent Education
The purpose of this study was to examine the effectiveness of providing extra time as an accommodation to students with learning disabilities (LD) in higher education institutions.
Juan Mendelsohn Ontong, Mareli Rossouw
doaj   +1 more source

Shared Vision and Autonomous Motivation versus Financial Incentives Driving Success in Corporate Acquisitions

Frontiers in Psychology, 2015
Successful corporate acquisitions require its managers to achieve substantial performance improvements in order to sufficiently cover acquisition premiums, the expected return of debt and equity investors, and the additional resources needed to capture ...
Byron C Clayton
doaj   +1 more source