Results 91 to 100 of about 17,437,503 (278)
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
SAGE OpenThis study intends to investigate how the extra-role behavior of distributors’ FFE strategic orientation affects daily necessity manufacturers’ NPD (New product development) performance.
Jiaxu Huang, Haiqing Hu
doaj +1 more source
DANP Composite Analysis of Spiritual Leadership Factors Based on Extra-Role Behaviors in Large Industries of Kerman Province [PDF]
رویکردهای نوین در مدیریت و بازاریابیThe purpose of the present study is DANP Composite Analysis of Spiritual Leadership Factors Based on Extra-Role Behaviors in Large Industries of Kerman Province.
Seyyed Mohammad Bagher Mansouri +4 more
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Extra Financial Analysis – EFA: Environmental and financial performances of ABB, Akzo-Nobel and SCA: Picturing the business opportunities and risks associated to stakeholder perceptions and environmental and social prerequisites [PDF]
External assessment of companies’ environmental aspects often focus on the existence of strategies, commitments, management systems and reporting of firms that concerns environmental aspects.
Belhaj, Mohammed, Cerin, Pontus
core
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Determining a Multi -Criterion Model to Evaluate the Public Companies of Iran [PDF]
مدیریت بهره وری, 2011 Organizational performance is one of the controversial and important issues which has always preoccupied the managers of different sectors. Different views have been presented on the evaluation of organizational performance and the related variables ...
Hasan Givarian, Firooz Dindar Farkoos
doaj
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Extra care housing: a paradigm shift [PDF]
, 2007 This paper sets out to investigate if and how a spatial typology for extra care housing (ECH) can be defined within the context of housing for older people in the UK.
Hanson, J., Wojgani, H.
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