Results 11 to 20 of about 2,813,323 (292)

Extracellular DNA metabolism in Haloferax volcanii [PDF]

open access: yesFrontiers in Microbiology, 2014
Extracellular DNA is found in all environments and is a dynamic component of the micro-bial ecosystem. Microbial cells produce and interact with extracellular DNA through many endogenous mechanisms.
Scott eChimileski   +4 more
doaj   +5 more sources

Extracellular DNA—A Danger Signal Triggering Immunothrombosis [PDF]

open access: yesFrontiers in Immunology, 2020
Clotting and inflammation are effective danger response patterns positively selected by evolution to limit fatal bleeding and pathogen invasion upon traumatic injuries.
Chongxu Shi   +3 more
doaj   +6 more sources

Soot and charcoal as reservoirs of extracellular DNA [PDF]

open access: yesPeer Community Journal, 2021
The vast potential of using sediment adsorbed DNA as a window to past and present biodiversity rely on the ability of solid surfaces to adsorb environmental DNA. However, a comprehensive insight into DNA adsorption at surfaces in general is lacking. Soot and charcoal are carbonaceous materials widespread in the environment where they readily can come ...
Stanislav Jelavić   +6 more
openaire   +8 more sources

Minimal Influence of Extracellular DNA on Molecular Surveys of Marine Sedimentary Communities [PDF]

open access: yesFrontiers in Microbiology, 2018
Extracellular DNA has been reported to comprise a large fraction of total DNA in near-seafloor sediment. However, the potential effect of extracellular DNA, arising from dead or moribund cells, on sequencing surveys is a critical concern that has largely
Gustavo A. Ramírez   +3 more
doaj   +2 more sources

Extracellular DNA-induced antimicrobial peptide resistance mechanisms in Pseudomonas aeruginosa. [PDF]

open access: yesFrontiers in Microbiology, 2013
Extracellular DNA (eDNA) is in the environment, bodily fluids, in the matrix of biofilms, and accumulates at infection sites. Extracellular DNA can function as a nutrient source, a universal biofilm matrix component and an innate immune effector in ...
Shawn eLewenza
doaj   +2 more sources

The Staphylococcus aureus Extracellular Adherence Protein Eap Is a DNA Binding Protein Capable of Blocking Neutrophil Extracellular Trap Formation

open access: yesFrontiers in Cellular and Infection Microbiology, 2018
The extracellular adherence protein (Eap) of Staphylococcus aureus is a secreted protein known to exert a number of adhesive and immunomodulatory properties. Here we describe the intrinsic DNA binding activity of this multifunctional secretory factor. By
Janina Eisenbeis   +10 more
doaj   +2 more sources

Extracellular DNA-protein interactions. [PDF]

open access: yesCurr Opin Struct Biol
Intracellular DNA primarily serves as the cellular genetic material both in eukaryotes and prokaryotes. This function is often regulated by alterations in the DNA structure to accommodate transcription, recombination, and DNA replication. Extracellularly, both eukaryotic and prokaryotic cells take advantage of DNA plenty in addition to a permissive ...
Goodman SD.
europepmc   +3 more sources

Dynamics of Urinary Extracellular DNA in Urosepsis. [PDF]

open access: yesBiomolecules, 2023
Extracellular DNA (ecDNA) is a promising candidate marker for the early diagnosis and monitoring of urinary tract infections (UTIs). The aim of our study is to describe the dynamics of ecDNA in the plasma and urine of patients with urosepsis as well as in a mouse model of UTI.
Mihaľová M   +6 more
europepmc   +4 more sources

In vivo evidence for extracellular DNA trap formation. [PDF]

open access: yes, 2020
Extracellular DNA trap formation is a cellular function of neutrophils, eosinophils, and basophils that facilitates the immobilization and killing of invading microorganisms in the extracellular milieu. To form extracellular traps, granulocytes release a
Simon, Hans-Uwe   +11 more
core   +3 more sources

Extracellular DNA and autoimmune diseases [PDF]

open access: yesCellular & Molecular Immunology, 2018
Extracellular DNA is secreted from various sources including apoptotic cells, NETotic neutrophils and bacterial biofilms. Extracellular DNA can stimulate innate immune responses to induce type-I IFN production after being endocytosed. This process is central in antiviral responses but it also plays important role in the pathogenesis of a range of ...
Hantao, Lou, Matthew C, Pickering
openaire   +2 more sources

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