Results 41 to 50 of about 2,813,323 (292)
The Role of Extracellular DNA in Autoimmunity in SLE [PDF]
AbstractSystemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterized by the expression of antibodies to DNA. These antibodies form immune complexes that can stimulate cytokine production as well as deposit in the tissues to incite inflammation and damage.
K-Y, Su, D S, Pisetsky
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Microbiome studies mostly rely on total DNA extracts obtained directly from environmental samples. The total DNA consists of both intra- and extracellular DNA, which differ in terms of their ecological interpretation.
Maraike Probst +4 more
doaj +1 more source
EXTRACELLULAR STIMULATION OF EPIDERMAL DNA SYNTHESIS
AbstractThe removal of the topmost cell layers of the epidermal stratum corneum by stripping initiates a series of biochemical events which alters the normal homeostatic control of and results in the acceleration of the cell cycle in basal cells which are ten to twenty cell layers removed from the site of stripping. One measure of accelerated events is
S, Rothberg +3 more
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The diverse roles of non-coding RNA and DNA in cross-species communication is yet to be revealed. Once thought to only involve intra-specifically in regulating gene expression, the evidence that these genetic materials can also modulate gene expression ...
Karlia Meitha +4 more
doaj +1 more source
Recent advances in molecular diagnostics have opened new avenues for integrating genetic and epigenetic bio- markers into clinical practice. Areas such as gene expression profiling, extracellular DNA quantification, and microRNA expression analysis have ...
D D. Velikiy +3 more
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Extracellular DNA is ubiquitous in soil and sediment and constitutes a dominant fraction of environmental DNA in aquatic systems. In theory, extracellular DNA is composed of genomic elements persisting at different degrees of preservation produced by ...
Aurèle Vuillemin +7 more
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The Role of DNA in the Extracellular Environment: A Focus on NETs, RETs and Biofilms
The capacity to actively release genetic material into the extracellular environment has been reported for bacteria, archaea, fungi, and in general, for microbial communities, but it is also described in the context of multicellular organisms, animals ...
Francesco Monticolo +7 more
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Dynamics of extracellular DNA in the marine environment [PDF]
The production and turnover of dissolved DNA in subtropical estuarine and oligotrophic oceanic environments were investigated. Actively growing heterotrophic bacterioplankton (i.e., those capable of [3H]thymidine incorporation) were found to produce dissolved DNA, presumably through the processes of death and lysis, grazing by bacteriovores, and ...
J H, Paul, W H, Jeffrey, M F, DeFlaun
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Objective of the study: to systematically evaluate the efficacy and safety of adjunctive distrept-enzymes H46A streptokinase-streptodornase therapy in women with gynecological disorders and to interpret the available clinical evidence within the context ...
V.V. Kaminskyi +5 more
doaj +1 more source
Extracellular DNA traps in allergic, infectzious, and autoimmune diseases
Extracellular DNA traps are part of the innate immune response and are seen with many infectious, allergic, and autoimmune diseases. They can be generated by several different leukocytes, including neutrophils, eosinophils, and monocytes, as well as mast
Simon, Hans-Uwe +5 more
core +1 more source

