Results 51 to 60 of about 2,813,323 (292)

Plasma DNA and deoxyribonuclease are associated with glucose metabolism in healthy mice.

PLoS ONE, 2022
It is currently unknown why obesity leads in some patients to prediabetes and metabolic syndrome. Microinflammation potentially caused by extracellular DNA is supposed to be involved.
Katarína Kmeťová, Jozef Čonka, Jakub Janko, Júlia Illés, Oľga Uličná, Peter Celec   +5 more
doaj   +1 more source

Arabidopsis thaliana response to extracellular DNA: self versus nonself exposure [PDF]

, 2021
The inhibitory effect of extracellular DNA (exDNA) on the growth of conspecific individuals was demonstrated in different kingdoms. In plants, the inhibition has been observed on root growth and seed germination, demonstrating its role in plant–soil ...
Mazzoleni S., Foscari A., Monticolo F., Bonanomi G., Benvenuto G., Esposito A., Vega-Munoz I., Termolino P., Heil M., Palomba E., Chiusano M. L., de Lorenzo G., Incerti G., Colantuono C., Marti L., Carteni F., Carteni Fabrizio, Esposito, Alfonso, Stefano Mazzoleni, Incerti, Guido, Giovanna Benvenuto, Isaac VegaMuñoz, Lucia Marti, Foscari, Alessandro, Heil, Martin, Benvenuto, Giovanna, de Lorenzo, Giulia, Pasquale Termolino, Monticolo, Francesco, Maria Luisa Chiusano, Guido Incerti, Chiusano, Maria Luisa, Incerti, G., Palomba, Emanuela, Mazzoleni, Stefano, Giulia de Lorenzo, Martin Heil, Alfonso Esposito, Giuliano Bonanomi, Marti, Lucia, Francesco Monticolo, Termolino, Pasquale, Isaac Vega-Muñoz, Fabrizio Carteni, Bonanomi, Giuliano, Chiara Colantuono, Emanuela Palomba, Vega-Muñoz, Isaac, Colantuono, Chiara, Carteni, Fabrizio, Alessandro Foscari, Giuliano Bonanomi andStefano Mazzoleni   +51 more
core   +2 more sources

The first clinical experience with selective DNA plasmasorption using the NucleoCapture Device in the treatment of systemic lupus erythematosus

Современная ревматология
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease of unknown etiology characterized by the overproduction of autoantibodies against various components of the nucleus of the patient's own cells with the development of immunoinflammatory ...
E. A. Aseeva, N. S. Pokrovsky, S. K. Soloviev, E. V. Nikolaeva, N. Yu. Nikishina, E. T. Abdullin, T.  M. Reshetnyak, E. G. Zotkin, A. M. Lila   +8 more
doaj   +1 more source

Mitochondrial DNA copy number level in the culture medium of human embryos as a factor in predicting the onset and prolongation of pregnancy

RUDN Journal of Medicine
Relevance. A key factor influencing the effectiveness of assisted reproductive technology programmes is the quality of the embryo transferred into the uterine cavity.
Olga I. Lisitsyna, Nataliya P. Makarova, Aleksey M. Krasnyi, Alexey N. Ekimov, Andrey Yu. Romanov, Nataliya V. Dolgushina   +5 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Qualitative and quantitative characteristics of the extracellular DNA delivered to the nucleus of a living cell

Cancer Cell International, 2006
Background The blood plasma and other intertissue fluids usually contain a certain amount of DNA, getting there due to a natural cell death in the organism.
Bogachev Sergei S, Sebeleva Tamara E, Mechetina Lyudmila V, Vratskikh Oksana, Likhacheva Anastasia, Rogachev Vladimir A, Yakubov Leonid A, Shurdov Mikhail A   +7 more
doaj   +1 more source

Extracellular DNA as an essential component and therapeutic target of microbial biofilm

, 2015
The dominant part of human infections is associated with biofilm formations. Biofilm represents structured communities of bacterial or fungal cells enclosed in self-produced polymeric matrixes adherent to supporting surfaces.
Marzena Wątek, Urszula Wnorowska, Katarzyna Niemirowicz, Ewelina Piktel, Robert Bucki, Bonita Durnaś, Katarzyna Głuszek   +6 more
core   +1 more source

A DNase encoded by integrated element CJIE1 inhibits natural transformation of Campylobacter jejuni [PDF]

, 2009
The species Campylobacter jejuni (C. jejuni) is considered naturally competent for DNA uptake and displays strong genetic diversity. Nevertheless, non-naturally transformable strains and several relatively stable clonal lineages exist.
Dep Infectieziekten Immunologie, Graaf-van Bloois, L., van der, Gaasbeek, E.J., Strategic Infection Biology, van Putten, J.P.M., van der Graaf-van Bloois, L., Wagenaar, J.A., Wösten, M.M.S.M., van der Wal, F.J., Wal, F.J., van der, Parker, C.T., Guilhabert, M.R., Putten, J.P.M., van   +12 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

The concept of natural genome reconstruction. Part 1. Basic provisions of the “natural genome reconstruction” concept. Changing the genome of hematopoietic stem cells using several natural cellular mechanisms that are inherent in the hematopoietic cell and determine its biological status as “the source of the body’s reparative potential”

Вавиловский журнал генетики и селекции
We present a series of articles proving the existence of a previously unknown mechanism of interaction between hematopoietic stem cells and extracellular double-stranded DNA (and, in particular, double-stranded DNA of the peripheral bloodstream), which ...
L. A. Yakubov, O. S. Taranov, S. V. Sidorov, S. D. Nikonov, A. A. Ostanin, E. R. Chernykh, N. A. Kolchanov, S. S. Bogachev   +7 more
doaj   +1 more source