Results 251 to 260 of about 3,140,793 (317)

Bioprinting Perfusable and Vascularized Skeletal Muscle Flaps for the Treatment of Volumetric Muscle Loss

Advanced Healthcare Materials, EarlyView.
Volumetric muscle loss (VML) due to trauma or surgery, often leads to physical impairments. Traditional treatments rely on autologous flaps, limited by muscle availability often leading to donor site morbidity. This study presents multimodal bioprinting as an innovative approach for fabricating vascularized muscle flaps with 3D‐printed macrovessels ...
Eliana O. Fischer, Anna Tsukerman, Majd Machour, Margarita Shuhmaher, Asaf Silverstein, Maya Yaakov, Orit Bar‐Am, Lior Debbi, Shulamit Levenberg   +8 more
wiley   +1 more source

Bone tissue in murine atypical type VI osteogenesis imperfecta has changes in vascular pores and matrix organization, plus classic OI hypermineralization

Bone Reports, 2020
Ghazal Hedjazi, Gali Guterman-Ram, Stéphane Blouin, Paul Roschger, Victoria Schemenz, Wolfgang Wagermaier, Peter Fratzl, Jochen Zwerina, Nadja Fratzl-Zelman, Joan C. Marini   +9 more
doaj  

Controlled delivery of PRP from decellularized extracellular matrix enhances skeletal muscle regeneration. [PDF]

Sci Rep
Erfanian S, Mostafaei F, Ajalloueian F, Baharvand H, Rajabi S, Ashtiani MK.   +5 more
europepmc   +1 more source

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

Advanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto, Moisés L. Pinto, Christian Serre   +2 more
wiley   +1 more source

Cartilage Intermediate Layer Protein-1 Promotes Extracellular Matrix Degeneration via Interacting With CD47. [PDF]

J Cell Mol Med
Deng J, Yang Y, Xiang Y, Luo F, Xu J, Zhang Z, He J.   +6 more
europepmc   +1 more source

Enhanced PDMS Functionalization for Organ‐on‐a‐Chip Platforms Using Ozone and Sulfo‐SANPAH: A Simple Approach for Biomimetic Long‐Term Cell Cultures

Advanced Healthcare Materials, EarlyView.
The use of organ‐on‐a‐chip (OOC) microfluidic platforms is expanding in biomedical research. While this emerging technology is becoming increasingly accessible, the stability of long‐term functional cultures remains a critical challenge to address. This study presents a straightforward, one‐step method for the functionalization of polydimethylsiloxane ...
Mitzi Pérez‐Calixto, Cindy Peto‐Gutiérrez, Alyssa Shapiro, Lazaro Huerta, Mathieu Hautefeuille, Marina Macías‐Silva, Daniel Pérez‐Calixto, Genaro Vázquez‐Victorio   +7 more
wiley   +1 more source

Compartment-Resolved Proteomics with Deep Extracellular Matrix Coverage. [PDF]

Bio Protoc
McCabe MC, Saviola AJ, Hansen KC.
europepmc   +1 more source

TPMS‐Gyroid Scaffold‐Mediated Up‐Regulation of ITGB1 for Enhanced Cell Adhesion and Immune‐Modulatory Osteogenesis

Advanced Healthcare Materials, EarlyView.
A) SLM generates biomimetic bone scaffolds with consistent porosity but varying TPMS‐Gyroid unit cell designs (TG15, TG20, TG25, TG30). B) By enhancing the expression of ITGB1, TPMS‐Gyroid scaffolds can facilitate osteogenic differentiation in BMSCs and promote M2 polarization in macrophages.
Jing Wang, Zenan Huang, Zhenzhong Han, Jing Luan, Zihan Li, Xutong Guo, Dongxu Yang, Yazhou Cui, Jinxiang Han, Duo Xu   +9 more
wiley   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Extracellular matrix turnover in severe COVID-19 is reduced by corticosteroids. [PDF]

Respir Res
Pillay J, Flikweert AW, van Meurs M, Grootenboers MJ, van der Sar-van der Brugge S, van der Voort PHJ, Karsdal MA, Sand JMB, Leeming DJ, Burgess JK, Moser J.   +10 more
europepmc   +1 more source