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Extracellular Matrix (ECM) Guides Tissue-Specific Function & Developmental Processes

, 1992
Bissell, M.J., Howlett, A.R., Streuli, C.H.   +2 more
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Decellularized Extracellular Matrix (ECM) as a Model to Study Fibrotic ECM Mechanobiology

2021
Aberrant deposition of the extracellular matrix (ECM) causes fibrosis and leads to ECM stiffening. This fibrotic ECM provides biological and biophysical stimulations to alter cell activity and drive progression of fibrosis. As an emerging discipline, mechanobiology aims to access the impact of both these cues on cell behavior and relates the ...
Chiuan-Ren, Yeh, Grace C, Bingham, Jagathpala, Shetty, Ping, Hu, Thomas H, Barker   +4 more
openaire   +2 more sources

Kinetics for De-Extracellular Matrix(ECM)

MRS Advances, 2018
A kinetic model for ECM decellularization with Trypsin and Deoxycholic Acid as reactants in a batch system has been developed. The decellularization mechanism has been analysed by solving a series of ordinary differential equations relating heterogeneous reaction kinetics at the solid/liquid interface to mass transfer of reactant and products. In order
Namsoo P. Kim, Jihye Kim, Guikuan Yue, Diana Cho   +3 more
openaire   +1 more source

Extracellular Matrix (ECM) and Cytoskeletal Modulation of Cellular Radiosensitivity

Acta Oncologica, 1997
Modulation of radiosensitivity by components of the extracellular matrix (ECM) and cytoskeletal elements has not been adequately studied. Although differences in the radiosensitivities of cells grown as monolayers, as spheroids, or grown in vitro in animal models are known, explanations have in the past neglected possible influences by the ECM and ...
A F, Stevenson, C S, Lange
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Extracellular matrix (ECM) stiffness and degradation as cancer drivers

Journal of Cellular Biochemistry, 2018
AbstractAlteration in the density and composition of extracellular matrix (ECM) occurs in tumors. The alterations toward both stiffness and degradation are contributed to tumor growth and progression. Cancer‐associated fibroblasts (CAFs) are the main contributors to ECM stiffness and degradation.
Masoud Najafi, Bagher Farhood, Keywan Mortezaee   +2 more
openaire   +2 more sources