Results 31 to 40 of about 5,777,110 (367)

Changes in diffusion through the brain extracellular space [PDF]

open access: green, 2004
ECS (extracellular space) works as the microenvironment of brain cells. Diffusion through ECS may be described through an effective diffusion coefficient, De, which in turn depends on ECS porosity, ε, and tortuosity, T. In the present research, diffusion
М. Мота   +3 more
openalex   +5 more sources

An Isotonic Model of Neuron Swelling Based on Co-Transport of Salt and Water

open access: yesMembranes, 2023
Neurons spend most of their energy building ion gradients across the cell membrane. During energy deprivation the neurons swell, and the concomitant mixing of their ions is commonly assumed to lead toward a Donnan equilibrium, at which the concentration ...
Reinoud Maex
doaj   +1 more source

Extracellular volume fraction using contrast-enhanced CT is useful in differentiating intrahepatic cholangiocellular carcinoma from hepatocellular carcinoma

open access: yesFrontiers in Oncology, 2023
ObjectivesTo evaluate whether tumor extracellular volume fraction (fECV) on contrast-enhanced computed tomography (CT) aids in the differentiation between intrahepatic cholangiocarcinoma (ICC) and hepatocellular carcinoma (HCC).MethodsIn this ...
T. Honda   +12 more
doaj   +1 more source

New Insights into Alzheimer’s Disease: Novel Pathogenesis, Drug Target and Delivery

open access: yesPharmaceutics, 2023
Alzheimer’s disease (AD), the most common type of dementia, is characterized by senile plaques composed of amyloid β protein (Aβ) and neurofilament tangles derived from the hyperphosphorylation of tau protein.
Haishu Chen   +7 more
doaj   +1 more source

Unconventional Pathways of Protein Secretion: Mammals vs. Plants

open access: yesFrontiers in Cell and Developmental Biology, 2022
In eukaryotes, many proteins contain an N-terminal signal peptide that allows their translocation into the endoplasmic reticulum followed by secretion outside the cell according to the classical secretory system. However, an increasing number of secreted
Elisa Maricchiolo   +5 more
doaj   +1 more source

What Triggers the Interictal Epileptic Spike? A Multimodal Multiscale Analysis of the Dynamic of Synaptic and Non-synaptic Neuronal and Vascular Compartments Using Electrical and Optical Measurements

open access: yesFrontiers in Neurology, 2021
Interictal spikes (IISs) may result from a disturbance of the intimate functional balance between various neuronal (synaptic and non-synaptic), vascular, and metabolic compartments.
Cristian Arnal-Real   +4 more
doaj   +1 more source

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